Evidence map›Paper›PMID 38585847›Full record

ArticleResearch square2024

Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma.

Timothy I Shaw, Stanley Pounds, Xueyuan Cao, Jing Ma, Gustavo Palacios, John Mason, Sherrie Perkins, Gang Wu, Yiping Fan, Jian Wang and 10 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 1 country.

Timothy I ShawDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-9316-1924
Stanley PoundsDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-9167-2114
Xueyuan CaoDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.
Jing MaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Gustavo PalaciosDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN.
John MasonDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Sherrie PerkinsDepartment of Pathology, University of Utah Health Sciences, Salt Lake City, UT.
Gang WuDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-1678-5864
Yiping FanDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Jian WangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Xin ZhouDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Alyssa ObermayerDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL.
Marsha C KinneyDepartment of Pathology and Laboratory Medicine, University of Texas Health Science Center, at San Antonio, San Antonio, TX.
Jacqueline KravekaDivision of Pediatric Hematology-Oncology, Medical University of South Carolina, Charleston, SC.
Thomas GrossDepartment of Pediatric Hematology-Oncology, Nationwide Children's Hospital, Columbus, OH.
John SandlundDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
Jinghui ZhangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-3350-9682
Charles MullighanDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-1871-1850
Megan S LimDepartment of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Vasiliki LeventakiDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
St. Jude Children's Research Hospital · USMoffitt Cancer Center · USMedical University of South Carolina · USMemorial Sloan Kettering Cancer Center · USNationwide Children's Hospital · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas MD Anderson Cancer Center · USUniversity of Tennessee Health Science Center · USUniversity of Utah · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI KENNETH Lynn WRIGHT · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

Anaplastic large cell lymphoma (ALCL) is a mature T-cell lymphoma that accounts for for 10-15% of childhood lymphomas. Despite the observation that more than 90% of pediatric cases harbor the anaplastic lymphoma kinase (

Identifiers

PMID38585847
PMCPMC10996813
OpenAlexW4393255479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.