Evidence map›Paper›PMID 38585813›Full record

ArticlebioRxiv : the preprint server for biology2024

Carbon dioxide shapes parasite-host interactions in a human-infective nematode.

Navonil Banerjee, Spencer S Gang, Michelle L Castelletto, Felicitas Ruiz, Elissa A Hallem

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Navonil BanerjeeDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0001-9613-5652
Spencer S GangDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0002-5907-0631
Michelle L CastellettoDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.
Felicitas RuizDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0003-2175-0356
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0003-0260-3174
University of California, Los Angeles · US

Funding

UCLA MSD ProgramR25GM055052 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BARBER, PAUL HENRY, HASSON, TAMA W. · 1996 to 2021
$9.2M
MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6M
Neural mechanisms of gas sensing in a human-infective wormR01DC021489 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ELISSA ANYON HALLEM · 2024 to 2026
$1.8M
Deciphering the responses of skin-penetrating nematodes to carbon dioxideF32AI147617 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BANERJEE, NAVONIL · 2019 to 2020
$129k
NIAID NIH HHS F32 AI147617NIAID NIH HHS T32 AI007323NIDCD NIH HHS R01 DC021489NIGMS NIH HHS R25 GM055052
6 · The paper itself

Abstract

Skin-penetrating nematodes infect nearly one billion people worldwide. The developmentally arrested infective larvae (iL3s) seek out hosts, invade hosts via skin penetration, and resume development inside the host in a process called activation. Activated infective larvae (iL3as) traverse the host body, ending up as parasitic adults in the small intestine. Skin-penetrating nematodes respond to many chemosensory cues, but how chemosensation contributes to host seeking, intra-host development, and intra-host navigation - three crucial steps of the parasite-host interaction - remains poorly understood. Here, we investigate the role of carbon dioxide (CO

Indexed as

activationBAG neuronscarbon dioxide responsechemotaxisGCY-9host seekingparasitic helminthparasitic nematodeStrongyloides stercoralis

Identifiers

PMID38585813
PMCPMC10996684
OpenAlexW4393360132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.