Evidence map›Paper›PMID 38585775›Full record

ArticleResearch square2024

A Toxic Sterolysin From a 1950s Culture of Gymnodinium Veneficum Ballantine.

Allen R Place, Josefina Ramos-Franco, Amanda L Waters, Mark T Hamann

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allen R PlaceUniversity of Maryland Center for Environmental Sciences.
Josefina Ramos-FrancoRush University Medical Center.
Amanda L WatersUniversity of Central Oklahoma.
Mark T HamannMedical University of South Carolina.
Rush University Medical Center · US

Funding

SOURCING, ACQUISITION AND DATABASE COREP20RR021929 · NCRR · UNIVERSITY OF MISSISSIPPI · PI DOERKSEN, ROBERT J · 2006 to 2010
$11.1M
ANTIAIDS AGENTS FROM MARINE ORGANISMSR01AI036596 · NIAID · UNIVERSITY OF MISSISSIPPI · PI HAMANN, MARK T · 2001 to 2007
$2.3M
Control of IP3R-Mediated Calcium ReleaseR01GM111397 · NIGMS · RUSH UNIVERSITY MEDICAL CENTER · PI CHEN, SUI RONG WAYNE, FILL, MICHAEL · 2015 to 2018
$1.6M
NCRR NIH HHS P20 RR021929NIAID NIH HHS R01 AI036596NIGMS NIH HHS R01 GM111397
6 · The paper itself

Abstract

In 1957 Abbott and Ballentine described a highly toxic activity from a dinoflagellate isolated from the English Channel. in 1949 by Mary Park. From a culture maintained at Plymouth Laboratory since 1950, we have been able to isolate two toxic molecules (Abbotoxin and 59-E-Chloro-Abbotoxin), determine the planar structures by analysis of HRMS and 1D and 2D NMR spectra and found them to be karlotoxin (KmTx) congeners. Both toxins kill larval zebrafish with symptoms identical to that described by Abbot and Ballantine for gobies (

Indexed as

KarlotoxinsMembrane PoresSterol Binding

Identifiers

PMID38585775
PMCPMC10996815
OpenAlexW4393147336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.