Evidence map›Paper›PMID 38585726›Full record

ArticlebioRxiv : the preprint server for biology2025

A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.

Bao V Nguyen, Can Özden, Kairong Dong, Oguz Can Koc, Ana P Torres-Ocampo, Noelle Dziedzic, Daniel Flaherty, Jian Huang, Saketh Sankara, Nikki Lyn Abromson and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Bao V NguyenMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-4693-3098
Can ÖzdenMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-5673-878X
Kairong DongMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.
Oguz Can KocMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.
Ana P Torres-OcampoMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0003-1223-7120
Noelle DziedzicMolecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0001-7517-1873
Daniel FlahertyDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.
Jian HuangChemistry-Biology Interface Training Program, University of Massachusetts, Amherst, MA 01003, USA.
Saketh SankaraDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.
Nikki Lyn AbromsonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0009-0002-4212-7547
Diana R TomchickDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-7529-4643
Rafael A FissoreDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Jianhan ChenDepartment of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-5281-1150
Scott C GarmanDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0001-9912-2670
Margaret M StrattonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0003-2686-9022
University of Massachusetts Amherst · US

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
Chemistry-Biology Interface Predoctoral Training GrantT32GM139789 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ERIC Robert STRIETER · 2021 to 2026
$3.4M
Unraveling the molecular events driven by CaMKII in Ca2+-coupled cellsR35GM145376 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Margaret M Stratton · 2022 to 2026
$2.1M
Disordered Proteins and Dynamic Interactions in Biology and Diseases.R35GM144045 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jianhan Chen · 2022 to 2026
$2.0M
A Pixel Array Detector System for Small Angle X-ray ScatteringS10OD018483 · OD · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI CLASSEN, SCOTT · 2014 to 2014
$998k
NIGMS NIH HHS P30 GM124169NIGMS NIH HHS R35 GM144045NIGMS NIH HHS R35 GM145376NIGMS NIH HHS T32 GM135096NIGMS NIH HHS T32 GM139789NIH HHS S10 OD018483
6 · The paper itself

Abstract

Memory formation, fertilization, and cardiac function rely on precise Ca

Identifiers

PMID38585726
PMCPMC10996533
OpenAlexW4393217980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.