Evidence map›Paper›PMID 38585720›Full record

ArticlebioRxiv : the preprint server for biology2024

The subcommissural organ regulates brain development via secreted peptides.

Tingting Zhang, Daosheng Ai, Pingli Wei, Ying Xu, Zhanying Bi, Fengfei Ma, Fengzhi Li, Xing-Jun Chen, Zhaohuan Zhang, Xiaoxiao Zou and 22 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors at 13 institutions in 2 countries.

Tingting ZhangAcademy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing 100871, China.
Daosheng AiAcademy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing 100871, China.
Pingli WeiDepartment of Chemistry and School of Pharmacy, University of Wisconsin-Madison, Wisconsin 53705, USA.
Ying XuSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Zhanying BiChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Fengfei MaDepartment of Chemistry and School of Pharmacy, University of Wisconsin-Madison, Wisconsin 53705, USA.
Fengzhi LiChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Xing-Jun ChenAcademy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing 100871, China.
Zhaohuan ZhangDepartment of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Xiaoxiao ZouChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Zongpei GuoChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Yue ZhaoChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Jun-Liszt LiAcademy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing 100871, China.
Meng YeChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Ziyan FengChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Xinshuang ZhangChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Lijun ZhengChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Jie YuChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Chunli LiNational Institute of Biological Sciences, Beijing, 102206, China.
Tianqi TuDepartment of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing 100053, China.
Hongkui ZengAllen Institute for Brain Science, Seattle, Washington 98109, USA.
Jianfeng LeiMedical Imaging laboratory of Core Facility Center, Capital Medical University, Beijing 100054, China.
Hongqi ZhangDepartment of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing 100053, China.
Tao HongDepartment of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, Beijing 100053, China.
Li ZhangChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Benyan LuoDepartment of Neurology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.
Zhen LiChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Chao XingEugene McDermott Center for Human Growth and Development, Department of Bioinformatics, School of Public Health, UT Southwestern Medical Center, Dallas, Texas 75390, USA.
Chenxi JiaState Key Laboratory of Proteomics, National Center for Protein Sciences-Beijing, Beijing Proteome Research Center, Beijing Institute of Lifeomics, Beijing 102206, China.
Lingjun LiDepartment of Chemistry and School of Pharmacy, University of Wisconsin-Madison, Wisconsin 53705, USA.
Wenzhi SunChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Woo-Ping GeChinese Institute for Brain Research, Beijing, Beijing 102206, China.
Capital Medical University · CNChinese Institute for Brain Research · CNPeking University · CNUniversity of Wisconsin–Madison · USAllen Institute for Brain Science · USAnhui Medical University · CNBeijing Proteome Research Center · CNMcGovern Institute for Brain Research · USNankai University · CNNational Institute of Biological Sciences, Beijing · CNShanghai Changzheng Hospital · CNSouthwestern Medical Center · USZhejiang University · CN

Funding

Mass Spectrometric Studies of Neuropeptides in FeedingR01DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2006 to 2026
$6.7M
Acquisition of a High-Field Dual Source FTICR-MS for Pharmaceutical ResearchS10RR029531 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2011 to 2011
$2.1M
NCRR NIH HHS S10 RR029531NIDDK NIH HHS R01 DK071801
6 · The paper itself

Abstract

The subcommissural organ (SCO) is a gland located at the entrance of the aqueduct of Sylvius in the brain. It exists in species as distantly related as amphioxus and humans, but its function is largely unknown. To explore its function, we compared transcriptomes of SCO and non-SCO brain regions and found three genes,

Identifiers

PMID38585720
PMCPMC10996762
OpenAlexW4393360109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.