ArticleFrontiers in microbiology2024
A Mendelian randomization investigation of the causal association between the gut microbiota and sleep disorders.
Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Longitudinal trends and causal relationships of depression, anxiety, and sleep quality among MSM newly diagnosed with HIV.Social psychiatry and psychiatric epidemiology · 2026Article
- Advances in understanding intestinal microbiota mechanisms and intervention strategies for anxiety, depression, sleep disorders, and constipation.Frontiers in microbiology · 2026Review
- Heterogeneity in the association between gut microbiota and insomnia moderated by Parkinson's disease status.Frontiers in cellular and infection microbiology · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Background: Increasing numbers of people are suffering from sleep disorders. The gut microbiota of these individuals differs significantly. However, no reports are available on the causal associations between specific gut microbiota and sleep disorders. Methods: Data on gut genera were obtained from the MiBioGen consortium. Twenty-four cohorts with 18,340 individuals of European origin were included. Sleep disorder data, which included 216,454 European individuals, were retrieved from the FinnGen Biobank. Subsequently, two-sample Mendelian randomization was performed to analyze associations between sleep disorders and specific components of the gut microbiota. Results: Inverse variance weighting (IVW) revealed a negative correlation between Conclusion: A significant causal relationship was found between four specific gut microbiota and sleep disorders. One family,
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