Evidence map›Paper›PMID 38585592›Full record

ArticleEuropean urology open science2024

Preparing for the Worst: Management and Predictive Factors of Open Conversion During Minimally Invasive Renal Tumor Surgery (UroCCR-135 Study).

Nicolas Branger, Nicolas Doumerc, Thibaut Waeckel, Pierre Bigot, Louis Surlemont, Sophie Knipper, Géraldine Pignot, François Audenet, Frank Bruyère, Alexis Fontenil and 17 more

Registry-linked trialAbstract read
In one paragraph

Article in European urology open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03293563 (UroCCR Database), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03293563 recruitingnot on this map

UroCCR Database: French Research Network for Kidney Cancer (National Multidisciplinary Clinical and Biological Database on Kidney Cancer)

TypeobservationalSponsorUniversity Hospital, BordeauxRan2011 to 2040Enrolled30,000ConditionsKidney CancerArmsRadical nephrectomy versus partial nephrectomy (according surgeon judgement)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Nicolas BrangerDepartment of Urology, Institut Paoli Calmettes, Marseille, France.
Nicolas DoumercDepartment of Urology, CHU Toulouse, Toulouse, France.
Thibaut WaeckelDepartment of Urology, CHU Caen, Caen, France.
Pierre BigotDepartment of Urology, CHU Angers, Angers, France.
Louis SurlemontDepartment of Urology, CHU Rouen, Rouen, France.
Sophie KnipperDepartment of Urology, Institut Paoli Calmettes, Marseille, France.
Géraldine PignotDepartment of Urology, Institut Paoli Calmettes, Marseille, France.
François AudenetDepartment of Urology, Hopital européen Georges Pompidou, Paris, France.
Frank BruyèreDepartment of Urology, CHU Tours, Tours, France.
Alexis FontenilDepartment of Urology, CHU Nîmes, Nîmes, France.
Bastien ParierDepartment of Urology, Hopital Bicêtre, Paris, France.
Cécile ChampyDepartment of Urology, Hopital Henri Mondor, Créteil, France.
Morgan RouprêtGRC 5 Predictive Onco-Uro, AP-HP, Urology, Pitie-Salpetriere Hospital, Sorbonne University, Paris, France.
Jean-Jacques PatardDepartment of Urology, CH Mont-de-Marsan, Mont-de-Marsan, France.
François HenonDepartment of Urology, CHU Lille, Lille France.
Gaëlle FiardDepartment of Urology, CHU Grenoble, Grenoble, France.
Julien GuillotreauDepartment of Urology, Clinique Pasteur, Toulouse, France.
Jean-Baptiste BeauvalDepartment of Urology, Clinique Croix du Sud, Toulouse, France.
Constance MichelDepartment of Urology, Hopital Saint-Joseph, Paris France.
Simon BernardeauDepartment of Urology, CHU Poitiers, Poitiers, France.
Fayek TahaDepartment of Urology, CHU Reims, Reims, France.
Richard MalletDepartment of Urology, Polyclinique Francheville, Périgueux, France.
Frederic PanthierDepartment of Urology, Hopital Tenon, Paris, France.
Laurent GuyDepartment of Urology, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Louis VignotDepartment of Urology, CHU Nice, Nice, France.
Zine-Eddine KheneDepartment of Urology, CHU Rennes, Rennes, France.
Jean-Christophe BernhardDepartment of Urology, CHU Bordeaux, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Data regarding open conversion (OC) during minimally invasive surgery (MIS) for renal tumors are reported from big databases, without precise description of the reason and management of OC. The objective of this study was to describe the rate, reasons, and perioperative outcomes of OC in a cohort of patients who underwent MIS for renal tumor initially. The secondary objective was to find the factors associated with OC. Methods: Between 2008 and 2022, of the 8566 patients included in the UroCCR project prospective database (NCT03293563), who underwent laparoscopic or robot-assisted minimally invasive partial (MIPN) or radical (MIRN) nephrectomy, 163 experienced OC. Each center was contacted to enlighten the context of OC: "emergency OC" implied an immediate life-threatening situation not reasonably manageable with MIS, otherwise "elective OC". To evaluate the predictive factors of OC, a 2:1 paired cohort on the UroCCR database was used. Key findings and limitations: The incidence rate of OC was 1.9% for all cases of MIS, 2.9% for MIRN, and 1.4% for MIPN. OC procedures were mostly elective (82.2%). The main reason for OC was a failure to progress due to anatomical difficulties (42.9%). Five patients (3.1%) died within 90 d after surgery. Increased body mass index (BMI; odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.01-1.09, Conclusions and clinical implications: In MIS for renal tumors, OC was a rare event (1.9%), caused by various situations, leading to impaired perioperative outcomes. Emergency OC occurred once every 300 procedures. Increased BMI and cT stage were independent predictive factors of OC. Patient summary: The incidence rate of open conversion (OC) in minimally invasive surgery for renal tumors is low. Only 20% of OC procedures occur in case of emergency, and others are caused by various situations. Increased body mass index and cT stage were independent predictive factors of OC.

Indexed as

Intraoperative complicationLaparoscopic surgeryOpen conversionRenal cancerRobot-assisted surgerySurgical complication

Identifiers

PMID38585592
PMCPMC10997889

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.