Evidence map›Paper›PMID 38585410›Full record

Review3 Biotech2024

Exploring the antioxidant potential of endophytic fungi: a review on methods for extraction and quantification of total antioxidant capacity (TAC).

Rita Onyekachukwu Asomadu, Timothy Prince Chidike Ezeorba, Tobechukwu Christian Ezike, Jude Obiorah Uzoechina

Abstract readReview
In one paragraph

Review in 3 Biotech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Bioactive Potentials of Endophytic FungusInternational journal of microbiology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Assessing metal-induced glycation in French fries.Metallomics : integrated biometal science · 2025
    Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rita Onyekachukwu Asomadu *Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Enugu, 410001 Nigeria.
Timothy Prince Chidike Ezeorba *Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Enugu, 410001 Nigeria.ORCID 0000-0002-7077-3282
Tobechukwu Christian EzikeDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Enugu, 410001 Nigeria.
Jude Obiorah UzoechinaDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Enugu, 410001 Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endophytic fungi have emerged as a significant source of natural products with remarkable bioactivities. Recent research has identified numerous antioxidant molecules among the secondary metabolites of endophytic fungi. These organisms, whether unicellular or micro-multicellular, offer the potential for genetic manipulation to enhance the production of these valuable antioxidant compounds, which hold promise for promoting health, vitality, and various biotechnological applications. In this study, we provide a critical review of methods for extracting, purifying, characterizing, and estimating the total antioxidant capacity (TAC) of endophytic fungi metabolites. While many endophytes produce metabolites similar to those found in plants with established symbiotic associations, we also highlight the existence of novel metabolites with potential scientific interest. Additionally, we discuss how advancements in nanotechnology have opened new avenues for exploring nanoformulations of endophytic metabolites in future studies, offering opportunities for diverse biological and industrial applications.

Indexed as

ABTSDPPHEndophyte solvent extracts and secondary metabolitesFRAPORACOxidative stressTotal flavonoid content (TFC)Total Phenolic content (TPC)

Identifiers

PMID38585410
PMCPMC10997672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.