Evidence map›Paper›PMID 38584841›Full record

ArticleOpen medicine (Warsaw, Poland)2024

Long non-coding RNA SRA1 suppresses radiotherapy resistance in esophageal squamous cell carcinoma by modulating glycolytic reprogramming.

Yurao Chen, Peng Fan, Zhenhai Chen, Zemao Zheng, Ming He, Xiang Zhao, Ronghuai Chen, Juan Yao, Zhaodong Yang

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Epigenomics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yurao ChenDepartment of Radiation Oncology, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Peng FanDepartment of General Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Zhenhai ChenDepartment of Thoracic Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Zemao ZhengDepartment of General Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Ming HeDepartment of General Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Xiang ZhaoDepartment of General Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Ronghuai ChenDepartment of General Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.
Juan YaoDepartment of Radiation Oncology, Huaian Cancer Hospital, Huaian, 223299, Jiangsu, China.
Zhaodong YangDepartment of Thoracic Surgery, Huaian Hospital of Huaian City, Huaian, 223299, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC), a highly aggressive subtype of esophageal cancer, is characterized by late-stage diagnosis and limited treatment options. Recent advancements in transcriptome sequencing technologies have illuminated the molecular intricacies of ESCC tumors, revealing metabolic reprogramming as a prominent feature. Specifically, the Warburg effect, marked by enhanced glycolysis, has emerged as a hallmark of cancer, offering potential therapeutic targets. In this study, we comprehensively analyzed bulk RNA-seq data from ESCC patients, uncovering elevated

Indexed as

ESCCglycolysisPKM2SRA1

Identifiers

PMID38584841
PMCPMC10998669

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.