Evidence map›Paper›PMID 38584269›Full record

ReviewConflict and health2024

The impact of conflict on infectious disease: a systematic literature review.

Valia Marou, Constantine I Vardavas, Katerina Aslanoglou, Katerina Nikitara, Zinovia Plyta, Jo Leonardi-Bee, Kirsty Atkins, Orla Condell, Favelle Lamb, Jonathan E Suk

Abstract readReview
In one paragraph

Review in Conflict and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. HIV/AIDS in Conflict-Affected Countries, 2024-2025.Journal of epidemiology and global health · 2026
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valia MarouSchool of Medicine, University of Crete, Heraklion, Crete, Greece.
Constantine I VardavasSchool of Medicine, University of Crete, Heraklion, Crete, Greece.
Katerina AslanoglouSchool of Medicine, University of Crete, Heraklion, Crete, Greece.
Katerina NikitaraSchool of Medicine, University of Crete, Heraklion, Crete, Greece.
Zinovia PlytaSchool of Medicine, University of Crete, Heraklion, Crete, Greece.
Jo Leonardi-BeeCentre for Evidence Based Healthcare, School of Medicine, University of Nottingham, Nottingham, UK.
Kirsty AtkinsCentre for Evidence Based Healthcare, School of Medicine, University of Nottingham, Nottingham, UK.
Orla CondellEmergency Preparedness and Response Support, European Centre for Disease Prevention and Control, Solna, Sweden.
Favelle LambEmergency Preparedness and Response Support, European Centre for Disease Prevention and Control, Solna, Sweden.
Jonathan E SukEmergency Preparedness and Response Support, European Centre for Disease Prevention and Control, Solna, Sweden. Jonathan.Suk@ecdc.europa.eu.

Funding

European Centre for Disease Prevention and Control contract No. 22 ECD.13154 within Framework contract ECDC/2019/001 Lot 1B
6 · The paper itself

Abstract

backgroundConflict situations, armed or not, have been associated with emergence and transmission of infectious diseases. This review aims to identify the pathways through which infectious diseases emerge within conflict situations and to outline appropriate infectious disease preparedness and response strategies.

methodsA systematic review was performed representing published evidence from January 2000 to October 2023. Ovid Medline and Embase were utilised to obtain literature on infectious diseases in any conflict settings. The systematic review adhered to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analysis). No geographical restrictions were imposed.

findingsOur review identified 51 studies covering AIDS, Hepatitis B, Tuberculosis, Cholera, Coronavirus 2, Ebola, Poliomyelitis, Malaria, Leishmaniasis, Measles, Diphtheria, Dengue and Acute Bacterial Meningitis within conflict settings in Europe, Middle East, Asia, and Africa since October 2023. Key factors contributing to disease emergence and transmission in conflict situations included population displacement, destruction of vital infrastructure, reduction in functioning healthcare systems and healthcare personnel, disruption of disease control programmes (including reduced surveillance, diagnostic delays, and interrupted vaccinations), reduced access by healthcare providers to populations within areas of active conflict, increased population vulnerability due to limited access to healthcare services, and disruptions in the supply chain of safe water, food, and medication. To mitigate these infectious disease risks reported preparedness and response strategies included both disease-specific intervention strategies as well as broader concepts such as the education of conflict-affected populations through infectious disease awareness programmes, investing in and enabling health care in locations with displaced populations, intensifying immunisation campaigns, and ensuring political commitment and intersectoral collaborations between governments and international organisations.

conclusionConflict plays a direct and indirect role in the transmission and propagation of infectious diseases. The findings from this review can assist decision-makers in the development of evidence-based preparedness and response strategies for the timely and effective containment of infectious disease outbreaks in conflict zones and amongst conflict-driven displaced populations.

fundingEuropean Centre for Disease Prevention and Control under specific contract No. 22 ECD.13,154 within Framework contract ECDC/2019/001 Lot 1B.

Indexed as

ConflictControlInfectious diseasesOutbreaksPreparednessPreventionStrategiesWar

Identifiers

PMID38584269
PMCPMC11000310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.