Evidence map›Paper›PMID 38583086›Full record

ArticleEuropean heart journal2024

Coronary bypass surgery guided by computed tomography in a low-risk population.

Patrick W Serruys, Shigetaka Kageyama, Giulio Pompilio, Daniele Andreini, Gianluca Pontone, Saima Mushtaq, Mark La Meir, Johan De Mey, Kaoru Tanaka, Torsten Doenst and 13 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04142021 (A Multicenter, Pilot Study to Evaluate Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04142021 unknown statusnot on this map

A Multicenter, Pilot Study to Evaluate Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)

TypeobservationalSponsorNational University of Ireland, Galway, IrelandRan2020 to 2022Enrolled114ConditionsCoronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart DiseasesArmsCoronary computed tomography angiography
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Inpatient cardiac computed tomography angiography in Germany between 2005 and 2023: a nationwide registry study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  3. Review
  4. Applications of coronary computed tomography angiography: a clinical cardiologist's point of view.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. The History of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  10. The role of cardiac imaging in the post-ISCHEMIA world.The British journal of radiology · 2025
    Review
  11. Review
  12. The REVOLUTION project: planning and performing surgical revascularization based solely on coronary computed tomography angiography.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  13. The era of interventional imaging has arrived: what role for computed tomography and magnetic resonance?European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  14. Utility of Cardiovascular CT in Ischemic Heart Disease.Echocardiography (Mount Kisco, N.Y.) · 2025
    Review
  15. The Role of Cardiac Computed Tomography Angiography in Risk Stratification for Coronary Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Patrick W SerruysCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.ORCID 0000-0002-9636-1104
Shigetaka KageyamaCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.ORCID 0000-0003-4982-3203
Giulio PompilioCentro Cardiologico Monzino, IRCCS, Monzino, Italy.ORCID 0000-0003-2581-5735
Daniele AndreiniDivision of Cardiology and Cardiac Imaging, IRCCS Galeazzi Sant'Ambrogio, Milan, Italy.ORCID 0000-0002-5996-9209
Gianluca PontoneCentro Cardiologico Monzino, IRCCS, Monzino, Italy.ORCID 0000-0002-1339-6679
Saima MushtaqCentro Cardiologico Monzino, IRCCS, Monzino, Italy.
Mark La MeirDepartment of Cardiac Surgery, Universitair Ziekenhuis Brussel, VUB, Brussels, Belgium.ORCID 0000-0002-6261-5110
Johan De MeyDepartment of Radiology, Universitair Ziekenhuis Brussel, VUB, Brussels, Belgium.ORCID 0000-0002-3601-3212
Kaoru TanakaDepartment of Radiology, University Hospital Brussels, Brussels, Belgium.ORCID 0000-0001-5533-3185
Torsten DoenstDepartment of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany.ORCID 0000-0002-6411-909X
Ulf TeichgräberDepartment of Radiology, University Hospital Jena, Jena, Germany.ORCID 0000-0002-4048-3938
Ulrich SchneiderDepartment of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany.
John D PuskasDepartment of Cardiovascular Surgery, Mount Sinai Morningside, New York, NY, USA.ORCID 0000-0003-0459-4750
Jagat NarulaUniversity of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-0280-3996
Himanshu GuptaDepartment of Radiology, The Valley Hospital, Ridgewood, NJ, USA.
Vikram AgarwalDepartment of Cardiovascular Surgery, Mount Sinai Morningside, New York, NY, USA.
Jonathon LeipsicSt. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Shinichiro MasudaCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.ORCID 0000-0002-2791-8538
Nozomi KotokuCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.ORCID 0000-0002-7712-3733
Tsung-Ying TsaiCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.
Scot GargDepartment of Cardiology, Royal Blackburn Hospital, Blackburn, UK.ORCID 0000-0002-8911-0278
Marie-Angele MorelCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.
Yoshinobu OnumaCORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, University Road, Galway H91 TK33, Ireland.ORCID 0000-0001-7702-0649

Funding

GE HealthCareHealthCareHeartFlow
6 · The paper itself

Abstract

BACKGROUND AND

aimsIn patients with three-vessel disease and/or left main disease, selecting revascularization strategy based on coronary computed tomography angiography (CCTA) has a high level of virtual agreement with treatment decisions based on invasive coronary angiography (ICA).

methodsIn this study, coronary artery bypass grafting (CABG) procedures were planned based on CCTA without knowledge of ICA. The CABG strategy was recommended by a central core laboratory assessing the anatomy and functionality of the coronary circulation. The primary feasibility endpoint was the percentage of operations performed without access to the ICA. The primary safety endpoint was graft patency on 30-day follow-up CCTA. Secondary endpoints included topographical adequacy of grafting, major adverse cardiac and cerebrovascular (MACCE), and major bleeding events at 30 days. The study was considered positive if the lower boundary of confidence intervals (CI) for feasibility was ≥75% (NCT04142021).

resultsThe study enrolled 114 patients with a mean (standard deviation) anatomical SYNTAX score and Society of Thoracic Surgery score of 43.6 (15.3) and 0.81 (0.63), respectively. Unblinding ICA was required in one case yielding a feasibility of 99.1% (95% CI 95.2%-100%). The concordance and agreement in revascularization planning between the ICA- and CCTA-Heart Teams was 82.9% with a moderate kappa of 0.58 (95% CI 0.50-0.66) and between the CCTA-Heart Team and actual treatment was 83.7% with a substantial kappa of 0.61 (95% CI 0.53-0.68). The 30-day follow-up CCTA in 102 patients (91.9%) showed an anastomosis patency rate of 92.6%, whilst MACCE was 7.2% and major bleeding 2.7%.

conclusionsCABG guided by CCTA is feasible and has an acceptable safety profile in a selected population of complex coronary artery disease.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseFeasibility StudiesAgedFemaleHumansMaleMiddle AgedProspective StudiesVascular PatencyCoronary artery bypass graftingCoronary computed tomographyFeasibilityFirst-in-humanProof-of-conceptSafety

Identifiers

PMID38583086
PMCPMC11129794

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.