Evidence map›Paper›PMID 38582937›Full record

ArticleIMA fungus2024

Apiospora arundinis, a panoply of carbohydrate-active enzymes and secondary metabolites.

Trine Sørensen, Celine Petersen, Asmus T Muurmann, Johan V Christiansen, Mathias L Brundtø, Christina K Overgaard, Anders T Boysen, Rasmus D Wollenberg, Thomas O Larsen, Jens L Sørensen and 2 more

Abstract read
In one paragraph

Article in IMA fungus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Trine SørensenDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.ORCID http://orcid.org/0000-0001-6396-5502
Celine PetersenDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Asmus T MuurmannDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Johan V ChristiansenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 221, Kongens Lyngby, 2800, Denmark.
Mathias L BrundtøDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Christina K OvergaardDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Anders T BoysenDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Rasmus D WollenbergDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark.
Thomas O LarsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 221, Kongens Lyngby, 2800, Denmark.
Jens L SørensenDepartment of Chemistry and Bioscience, Aalborg University, Niels-Bohrs Vej 8, Esbjerg, 6700, Denmark.
Kåre L NielsenDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark. kln@bio.aau.dk.
Teis E SondergaardDepartment of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, Aalborg, 9220, Denmark. tes@bio.aau.dk.

Funding

Novo Nordisk Fonden NNF18OC0034952
6 · The paper itself

Abstract

The Apiospora genus comprises filamentous fungi with promising potential, though its full capabilities remain undiscovered. In this study, we present the first genome assembly of an Apiospora arundinis isolate, demonstrating a highly complete and contiguous assembly estimated to 48.8 Mb, with an N99 of 3.0 Mb. Our analysis predicted a total of 15,725 genes, with functional annotations for 13,619 of them, revealing a fungus capable of producing very high amounts of carbohydrate-active enzymes (CAZymes) and secondary metabolites. Through transcriptomic analysis, we observed differential gene expression in response to varying growth media, with several genes related to carbohydrate metabolism showing significant upregulation when the fungus was cultivated on a hay-based medium. Finally, our metabolomic analysis unveiled a fungus capable of producing a diverse array of metabolites.

Indexed as

ApiosporaArthriniumCAZymesOxford Nanopore sequencingSecondary metabolites

Identifiers

PMID38582937
PMCPMC10999098

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.