Evidence map›Paper›PMID 38582923›Full record

ArticleScientific reports2024

Enhancing astaxanthin biosynthesis and pathway expansion towards glycosylated C40 carotenoids by Corynebacterium glutamicum.

Vanessa L Göttl, Florian Meyer, Ina Schmitt, Marcus Persicke, Petra Peters-Wendisch, Volker F Wendisch, Nadja A Henke

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Response surface-based media optimization for astaxanthin production inFrontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Vanessa L GöttlGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Florian MeyerGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Ina SchmittGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Marcus PersickeCeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Petra Peters-WendischGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Volker F WendischGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany.
Nadja A HenkeGenetics of Prokaryotes, Faculty of Biology and CeBiTec, Bielefeld University, 33615, Bielefeld, Germany. nadja.henke@kit.edu.ORCID 0000-0002-1304-6310
Bielefeld University · DEKarlsruhe Institute of Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astaxanthin, a versatile C40 carotenoid prized for its applications in food, cosmetics, and health, is a bright red pigment with powerful antioxidant properties. To enhance astaxanthin production in Corynebacterium glutamicum, we employed rational pathway engineering strategies, focused on improving precursor availability and optimizing terminal oxy-functionalized C40 carotenoid biosynthesis. Our efforts resulted in an increased astaxanthin precursor supply with 1.5-fold higher β-carotene production with strain BETA6 (18 mg g

Indexed as

CarotenoidsCorynebacterium glutamicumbeta CaroteneMetabolic EngineeringXanthophyllsastaxanthinebeta CaroteneCarotenoidsXanthophyllsAstaxanthinCorynebacterium glutamicumFed-batch fermentationGlycosylated carotenoidsPathway engineering

Identifiers

PMID38582923
PMCPMC10998873
OpenAlexW4394012265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.