ArticleCommunications biology2024
Functional and structural reorganization in brain tumors: a machine learning approach using desynchronized functional oscillations.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Trimodal ultrasound imaging of brain-tumor interaction.iScience · 2026Article
- Functionally Informed Hand Knob Reveals Structural Connectome Differences in Motor-Eloquent Tumours.Cancers · 2026Article
- Exploring Links between Brain Image-Derived Phenotypes and Accelerometer-Measured Physical Activity in the UK Biobank.bioRxiv : the preprint server for biology · 2026Article
- A non-local diffusion magnetic resonance imaging tract density biomarker to stratify, predict, and interpret survival rates in human glioblastoma.Neuro-oncology · 2026Article
- Theoretical, Technical, and Analytical Foundations of Task-Based and Resting-State Functional Magnetic Resonance Imaging (fMRI)-A Narrative Review.Biomedicines · 2026Review
- Giant Right Sphenoid Wing Meningioma as a Reversible Frontal Network Lesion: A Pseudo-bvFTD Case with Venous-Sparing Skull-Base Resection.Diagnostics (Basel, Switzerland) · 2026Article
- Real-time augmented reality navigation in brain glioma resection: a pilot feasibility study.Frontiers in surgery · 2026Article
- Advances in Preoperative and Intraoperative Technologies for Safe Resection of Gliomas in Cognitive Regions.Cancers · 2025Review
- Structural-functional fingerprinting for abnormalities investigation in glioma patients.Scientific reports · 2025Article
- The Evolving Landscape of Radiomics in Gliomas: Insights into Diagnosis, Prognosis, and Research Trends.Cancers · 2025Review
- Denoising strategies of functional connectivity MRI data in lesional and non-lesional brain diseases.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Editorial: Spatiotemporal & AI trends in neuroscience, neuroimaging, and neurooncology.Frontiers in neuroimaging · 2025Article
- Reshaped functional connectivity gradients in acute ischemic stroke.NeuroImage. Clinical · 2025Article
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Authors and funding
4 authors.
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Abstract
Neuroimaging studies have allowed for non-invasive mapping of brain networks in brain tumors. Although tumor core and edema are easily identifiable using standard MRI acquisitions, imaging studies often neglect signals, structures, and functions within their presence. Therefore, both functional and diffusion signals, as well as their relationship with global patterns of connectivity reorganization, are poorly understood. Here, we explore the functional activity and the structure of white matter fibers considering the contribution of the whole tumor in a surgical context. First, we find intertwined alterations in the frequency domain of local and spatially distributed resting-state functional signals, potentially arising within the tumor. Second, we propose a fiber tracking pipeline capable of using anatomical information while still reconstructing bundles in tumoral and peritumoral tissue. Finally, using machine learning and healthy anatomical information, we predict structural rearrangement after surgery given the preoperative brain network. The generative model also disentangles complex patterns of connectivity reorganization for different types of tumors. Overall, we show the importance of carefully designing studies including MR signals within damaged brain tissues, as they exhibit and relate to non-trivial patterns of both structural and functional (dis-)connections or activity.
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