Evidence map›Paper›PMID 38582858›Full record

ArticleBMC infectious diseases2024

Molecular epidemiology of carbapenem-resistant gram-negative bacilli in Ecuador.

Claudia Soria-Segarra, Carmen Soria-Segarra, Marcos Molina-Matute, Ivanna Agreda-Orellana, Tamara Núñez-Quezada, Kerly Cevallos-Apolo, Marcela Miranda-Ayala, Grace Salazar-Tamayo, Margarita Galarza-Herrera, Victor Vega-Hall and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Co-occurrence of blaBMC microbiology · 2026
    Article
  2. Article
  3. Antimicrobial potential of compounds from the MMV pandemic response box and COVID box against carbapenem-resistant Acinetobacter baumannii.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Claudia Soria-SegarraSosecali, Medical Services, Guayaquil, EC, 090308, Ecuador. Claudia.soria.s@gmail.com.ORCID http://orcid.org/0000-0003-0896-6291
Carmen Soria-SegarraSosecali, Medical Services, Guayaquil, EC, 090308, Ecuador.
Marcos Molina-MatuteHospital del Río, Cuenca, Ecuador.
Ivanna Agreda-OrellanaHospital del Río, Cuenca, Ecuador.
Tamara Núñez-QuezadaHospital del Instituto Ecuatoriano de Seguridad Social Dr. Teodoro Maldonado Carbo, Guayaquil, Ecuador.
Kerly Cevallos-ApoloHospital de Infectología Dr. José Daniel Rodríguez Maridueña, Guayaquil, Ecuador.
Marcela Miranda-AyalaOmni Hospital, Guayaquil, Ecuador.
Grace Salazar-TamayoHospital Vozandez, Quito, Ecuador.
Margarita Galarza-HerreraHospital Eugenio Espejo, Quito, Ecuador.
Victor Vega-HallInterhospital, Guayaquil, Ecuador.
José E VillacisCentro de Investigación Para La Salud en América Latina (CISeAL), Pontificia Universidad Católica del Ecuador, Quito, 1701-2184, Ecuador.
José Gutiérrez-FernándezDepartment of Microbiology, School of Medicine and PhD Program in Clinical Medicine and Public Health, University of Granada & ibs, Granada, Spain.
Universidad de Granada · ESHospital Vozandes · ECInstituto Ecuatoriano de Enfermedades Digestivas · ECKennedy Clinic Hospital · ECPontificia Universidad Católica del Ecuador · EC

Funding

Pfizer Cia. LTDA 68213903
6 · The paper itself

Abstract

introductionCarbapenem-resistant gram-negative bacilli are a worldwide concern because of high morbidity and mortality rates. Additionally, the increasing prevalence of these bacteria is dangerous. To investigate the extent of antimicrobial resistance and prioritize the utility of novel drugs, we evaluated the molecular characteristics and antimicrobial susceptibility profiles of carbapenem-resistant Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii in Ecuador in 2022.

methodsNinety-five clinical isolates of carbapenem non-susceptible gram-negative bacilli were collected from six hospitals in Ecuador. Carbapenem resistance was confirmed with meropenem disk diffusion assays following Clinical Laboratory Standard Institute guidelines. Carbapenemase production was tested using a modified carbapenemase inactivation method. Antimicrobial susceptibility was tested with a disk diffusion assay, the Vitek 2 System, and gradient diffusion strips. Broth microdilution assays were used to assess colistin susceptibility. All the isolates were screened for the bla

resultsCarbapenemase production was observed in 96.84% of the isolates. The bla

conclusionThe epidemiology of carbapenem resistance in Ecuador is dominated by carbapenemase-producing K. pneumoniae harbouring bla

Indexed as

beta-LactamasesCarbapenemsAnti-Bacterial AgentsBacterial ProteinsEcuadorGram-Negative BacteriaHumansKlebsiella pneumoniaeMeropenemMicrobial Sensitivity TestsMolecular EpidemiologyPseudomonas aeruginosaAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsMeropenemCarbapenemase genesCarbapenem resistanceEcuadorGram-negative bacilli

Identifiers

PMID38582858
PMCPMC10998298
OpenAlexW4394012952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.