Evidence map›Paper›PMID 38582444›Full record

ArticleResuscitation2024

Association between survival and number of shocks for pulseless ventricular arrhythmias during pediatric in-hospital cardiac arrest in a national registry.

Sarah E Haskell, Derek Hoyme, M Bridget Zimmerman, Ron Reeder, Saket Girotra, Tia T Raymond, Ricardo A Samson, Marc Berg, Robert A Berg, Vinay Nadkarni and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Resuscitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Sarah E HaskellUniversity of Iowa Carver College of Medicine, Iowa City, IA, United States. Electronic address: sarah-haskell@uiowa.edu.
Derek HoymeUniversity of Wisconsin Madison School of Medicine, Madison, WI, United States.
M Bridget ZimmermanUniversity of Iowa College of Public Health, Iowa City, IA, United States.
Ron ReederUniversity of Utah School of Medicine, Salt Lake City, UT, United States.
Saket GirotraUT Southwestern Medical Center, Dallas, TX, United States.
Tia T RaymondMedical City Children's Hospital, Dallas, TX, United States.
Ricardo A SamsonChildren's Heart Center, Nevada, Las Vegas, NV, United States.
Marc BergStanford School of Medicine, Palo Alto, CA, United States.
Robert A BergChildren's Hospital of Philadelphia, Philadelphia, PA, United States.
Vinay NadkarniChildren's Hospital of Philadelphia, Philadelphia, PA, United States.
Dianne L AtkinsUniversity of Iowa Carver College of Medicine, Iowa City, IA, United States.
American Heart Association's Get With The Guidelines®-Resuscitation Investigators
University of Iowa · USChildren's Hospital of Philadelphia · USChildren's Heart Center Nevada · USMedical City Children's Hospital · USSouthwestern Medical Center · USStanford Medicine · USUniversity of Utah · USUniversity of Wisconsin–Madison · US

Funding

University of Iowa Institute for Clinical and Translational ScienceUM1TR004403 · NCATS · UNIVERSITY OF IOWA · PI Marlan R Hansen, Patricia Winokur · 2023 to 2026
$16.1M
NCATS NIH HHS UM1 TR004403University of Iowa Clinical and Translation Science Institute (NIH CTSA program UM1TR004403
6 · The paper itself

Abstract

backgroundAnnually 15,200 children suffer an in-hospital cardiac arrest (IHCA) in the US. Ventricular fibrillation or pulseless ventricular tachycardia (VF/pVT) is the initial rhythm in 10-15% of these arrests. We sought to evaluate the association of number of shocks and early dose escalation with survival for initial VF/pVT in pediatric IHCA.

methodsUsing 2000-2020 data from the American Heart Association's (AHA) Get with the Guidelines®-Resuscitation (GWTG-R) registry, we identified children >48 hours of life and ≤18 years who had an IHCA from initial VF/pVT and received defibrillation.

resultsThere were 251 subjects (37.7%) who received a single shock and 415 subjects (62.3%) who received multiple shocks. Baseline and cardiac arrest characteristics did not differ between those who received a single shock versus multiple shocks except for duration of arrest and calendar year. The median first shock dose was consistent with AHA dosing recommendations and not different between those who received a single shock versus multiple shocks. Survival was improved for those who received a single shock compared to multiple shocks. However, no difference in survival was noted between those who received 2, 3, or ≥4 shocks. Of those receiving multiple shocks, no difference was observed with early dose escalation.

conclusionsIn pediatric IHCA, most patients with initial VF/pVT require more than one shock. No distinctions in patient or pre-arrest characteristics were identified between those who received a single shock versus multiple shocks. Subjects who received a single shock were more likely to survive to hospital discharge even after adjusting for duration of resuscitation.

Indexed as

Cardiopulmonary ResuscitationElectric CountershockHeart ArrestRegistriesTachycardia, VentricularVentricular FibrillationAdolescentChildChild, PreschoolFemaleHumansInfantMaleUnited StatesCardiac arrestDefibrillationHospital qualityPediatricsSafetyVentricular arrhythmias

Identifiers

PMID38582444
PMCPMC12150816
OpenAlexW4393950899

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.