Evidence map›Paper›PMID 38582261›Full record

ArticleAlcohol (Fayetteville, N.Y.)2024

Emerging concepts in alcohol, infection & immunity: A summary of the 2023 alcohol and immunology research interest group (AIRIG) meeting.

Lauren N Rutt, Mengfei Liu, Esther Melamed, Shannon Twardy, Jamie L Sturgill, Lisa A Brenner, Josiah Hardesty, Steven A Weinman, Madison M Tschann, Jared Travers and 10 more

Open access · greenAbstract readConference Proceedings
PubMed Full text at PMC Publisher
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 1 country.

Lauren N RuttDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Mengfei LiuDigestive Diseases, Yale School of Medicine, New Haven, CT, USA.
Esther MelamedDepartment of Neurology, The University of Texas at Austin, Austin, TX, USA.
Shannon TwardyDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Jamie L SturgillDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY, USA.
Lisa A BrennerVA Rocky Mountain Mental Illness Research Education and Clinical Center, Rocky Mountain Regional Veterans Affairs (VA) Medical Center, Aurora, CO, USA; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Psychiatry and Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Military and Veteran Microbiome: Consortium for Research and Education, Aurora, CO, USA; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Josiah HardestyDepartment of Pharmacology and Toxicology, University of Louisville, Louisville, KY, USA.
Steven A WeinmanDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, MO, USA.
Madison M TschannDepartment of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA.
Jared TraversDivision of Gastroenterology and Liver Disease, Case Western Reserve University, Cleveland, OH, USA; University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
David A WelshDepartment of Medicine, Section of Pulmonary and Critical Care Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Natalie ChichettoDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL, USA.
Kathryn M CrottyDepartment of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University, Atlanta, GA, USA; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA.
Bryan MackowiakLaboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Samantha M YeligarDepartment of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep, Emory University, Atlanta, GA, USA; Atlanta Veterans Affairs Medical Center, Decatur, GA, USA.
Todd A WyattPulmonary Critical Care, Sleep & Allergy Division, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA; Research Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, USA; Department of Environmental, Agricultural and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA.
Rachel H McMahanDivision of GI Trauma and Endocrine Surgery, Department of Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Mashkoor A ChoudryDepartment of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA; Alcohol Research Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA.
Elizabeth J KovacsDivision of GI Trauma and Endocrine Surgery, Department of Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Veterans Health Administration, Eastern Colorado Health Care System, Rocky Mountain Regional Veterans Affairs Medical Center (RMRVAMC), Aurora, CO, USA; Alcohol Research Program, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Rebecca L McCulloughDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Alcohol Research Program, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: Rebecca.McCullough@CUanschutz.edu.
University of Colorado Anschutz Medical Campus · USEmory University · USLoyola University Chicago · USLouisiana State University Health Sciences Center New Orleans · USNational Institutes of Health · USNebraska Medical Center · USRocky Mountain MS Center · USThe University of Texas at Austin · USUniversity Hospitals of Cleveland · USUniversity of Florida · USUniversity of Kansas Medical Center · USUniversity of Kentucky · USUniversity of Louisville · USVeterans Health Administration · USYale University · US

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 2004 to 2026
$42.6M
PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI Samar Ibrahim · 2009 to 2026
$22.2M
Project Two - Exercise Training Decreases Alcohol Drinking by an FGF21-Dependent MechanismP50AA024333 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI Srinivasan Dasarathy · 2016 to 2026
$19.6M
longitudinal assessment of stress and stress-related concepts across a behavioral weight loss interventionP20GM144269 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Ilce Gabriela Medina-Meza, John P Thyfault · 2022 to 2026
$14.9M
Role of alcohol adapted Kupffer cells in the progression and resolution of ALDR01AA012863 · NIAAA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI STEVEN A WEINMAN · 2000 to 2026
$10.2M
Supplement: CoPARC: Colorado Pulmonary Alcohol Research CollaborativeR24AA019661 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM · 2011 to 2026
$8.5M
PILOT--IMPACT OF ALCOHOLISM ON AIDS ASOCIATED MUSCLE WASTINGP50AA009803 · NIAAA · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI NELSON, STEVE · 1994 to 2003
$7.2M
Graduate Training in the Pharmacological StudiesT32GM008602 · NIGMS · EMORY UNIVERSITY · PI HALL, RANDY A. · 1996 to 2021
$5.1M
Impact of chronic ethanol consumption on lung functional and immunological landscape and implication for susceptibility to SARSCoV2 infectionR01AA028735 · NIAAA · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM, VARLAMOV, OLEG · 2020 to 2025
$4.4M
Training in Neuroimmunoendocrine Effects of AlcoholT32AA013527 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2002 to 2021
$4.4M
Alcohol and Burn Trauma: Multi-organ Inflammatory ResponsesR35GM131831 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI ELIZABETH J. KOVACS · 2019 to 2026
$3.5M
Transcriptional and non-transcriptional functions of IRF3 in ALDR01AA027456 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI LAURA E. NAGY · 2019 to 2026
$3.5M
BLRD VA I01 BX004335BLRD VA I01 BX004694BLRD VA I01 BX005886BLRD VA IK6 BX005962CSRD VA IK2 CX000643NIAAA NIH HHS F31 AA029938NIAAA NIH HHS F31 AA031426NIAAA NIH HHS K01 AA029042NIAAA NIH HHS K08 AA027837NIAAA NIH HHS K08 AA030587NIAAA NIH HHS K99 AA030627NIAAA NIH HHS P50 AA009803NIAAA NIH HHS P50 AA024333NIAAA NIH HHS P60 AA009803NIAAA NIH HHS R00 AA025386NIAAA NIH HHS R00 AA030627NIAAA NIH HHS R01 AA012863NIAAA NIH HHS R01 AA026086NIAAA NIH HHS R01 AA027456NIAAA NIH HHS R01 AA028735NIAAA NIH HHS R01 AA030741NIAAA NIH HHS R13 AA020768NIAAA NIH HHS R21 AA025806NIAAA NIH HHS R24 AA019661NIAAA NIH HHS T32 AA013527NIDDK NIH HHS P30 DK084567NIEHS NIH HHS R21 ES032529NIGMS NIH HHS P20 GM144269NIGMS NIH HHS R35 GM131831NIGMS NIH HHS T32 GM008602
6 · The paper itself

Abstract

On December 8th 2023, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at the University of Colorado Anschutz Medical Campus in Aurora, Colorado. The 2023 meeting focused broadly on how acute and chronic alcohol exposure leads to immune dysregulation, and how this contributes to damage in multiple tissues and organs. These include impaired lung immunity, intestinal dysfunction, autoimmunity, the gut-Central Nervous System (CNS) axis, and end-organ damage. In addition, diverse areas of alcohol research covered multiple pathways behind alcohol-induced cellular dysfunction, including inflammasome activation, changes in miRNA expression, mitochondrial metabolism, gene regulation, and transcriptomics. Finally, the work presented at this meeting highlighted novel biomarkers and therapeutic interventions for patients suffering from alcohol-induced organ damage.

Indexed as

EthanolAlcoholismHumansInfectionsEthanolAlcoholComplosomeImmunoglobulinsImmunometabolismInfectionLung

Identifiers

PMID38582261
PMCPMC11179971
OpenAlexW4393952484

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.