Evidence map›Paper›PMID 38582017›Full record

ReviewCurrent opinion in chemical biology2024

Chemical biology tools to probe bacterial glycans.

Daniel Calles-Garcia, Danielle H Dube

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Dysregulation of a nucleotidyltransferase induces division and surface glycan defects inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel Calles-GarciaDepartment of Chemistry and Biochemistry, Bowdoin College, 6600 College Station, Brunswick, ME 04011, USA.
Danielle H DubeDepartment of Chemistry and Biochemistry, Bowdoin College, 6600 College Station, Brunswick, ME 04011, USA. Electronic address: ddube@bowdoin.edu.
Bowdoin College · US

Funding

Deciphering Helicobacter pylori's glycocode: uncovering & harnessing drug targetsR15GM109397 · NIGMS · BOWDOIN COLLEGE · PI DUBE, DANIELLE H. · 2015 to 2021
$1.1M
NIGMS NIH HHS R15 GM109397
6 · The paper itself

Abstract

Bacterial cells are covered by a complex carbohydrate coat of armor that allows bacteria to thrive in a range of environments. As a testament to the importance of bacterial glycans, effective and heavily utilized antibiotics including penicillin and vancomycin target and disrupt the bacterial glycocalyx. Despite their importance, the study of bacterial glycans lags far behind their eukaryotic counterparts. Bacterial cells use a large palette of monosaccharides to craft glycans, leading to molecules that are significantly more complex than eukaryotic glycans and that are refractory to study. Fortunately, chemical tools designed to probe bacterial glycans have yielded insights into these molecules, their structures, their biosynthesis, and their functions.

Indexed as

BacteriaAnti-Bacterial AgentsHumansMolecular ProbesPolysaccharidesPolysaccharides, BacterialAnti-Bacterial AgentsMolecular ProbesPolysaccharidesPolysaccharides, BacterialAzidesBacterial glycansBioorthogonal chemistryCarbohydratesClick chemistryLectinsMetabolic glycan labeling

Identifiers

PMID38582017
PMCPMC11164641
OpenAlexW4394006656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.