Evidence map›Paper›PMID 38581649›Full record

ReviewACS chemical biology2024

Protein-Based Tools for Studying Neuromodulation.

Wenjing Wang

Open access · greenAbstract readReview
In one paragraph

Review in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Wenjing WangLife Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United States.ORCID 0000-0001-6025-9848
University of Michigan · US

Funding

New classes of optogenetic and chemogenetic tools with a feedback controlDP2MH132939 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, WENJING · 2022 to 2025
$2.3M
Design of genetically encoded sensors for detecting endogenous opioid peptidesR01DA053200 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Wenjing Wang · 2022 to 2026
$1.7M
Design and characterization of Nanobodies to dementia-related α-synuclein strains in Parkinson’s diseaseR21AG072009 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, WENJING · 2021 to 2021
$454k
NIA NIH HHS R21 AG072009NIDA NIH HHS R01 DA053200NIMH NIH HHS DP2 MH132939
6 · The paper itself

Abstract

Neuromodulators play crucial roles in regulating neuronal activity and affecting various aspects of brain functions, including learning, memory, cognitive functions, emotional states, and pain modulation. In this Account, we describe our group's efforts in designing sensors and tools for studying neuromodulation. Our lab focuses on developing new classes of integrators that can detect neuromodulators across the whole brain while leaving a mark for further imaging analysis at high spatial resolution. Our lab also designed chemical- and light-dependent protein switches for controlling peptide activity to potentially modulate the endogenous receptors of the neuromodulatory system in order to study the causal effects of selective neuronal pathways.

Indexed as

BrainNeuronsNeurotransmitter AgentsNeurotransmitter Agents

Identifiers

PMID38581649
PMCPMC11129172
OpenAlexW4394014648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.