Evidence map›Paper›PMID 38581468›Full record

ArticleInternational orthopaedics2024

Spinal dysraphism in congenital scoliosis and kyphosis: a retrospective analysis in an Indian population.

Ashok N Johari, Amit Nemade, Arjun Dhawale, Farokh Wadia, Maulin Shah

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Article in International orthopaedics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ashok N JohariChildren's Orthopaedic Centre, Mumbai, India.
Amit NemadeDepartment of Orthopedics, N K P Salve Institute of Medical Sciences & Research Centre, Nagpur, India.
Arjun DhawaleDepartment of Orthopaedics, Sir H N Reliance Foundation Hospital and B.J. Wadia Hospital for Children, Mumbai, India. arjundhawale@hotmail.com.ORCID 0000-0002-8561-9157
Farokh WadiaSouthampton Children's Hospital, Southampton, UK.
Maulin ShahOrthokids Clinic, Ahmedabad, India.
Diabetes Care & Hormone Clinic · INInstitute of Medical Sciences · INSir H.N. Reliance Foundation Hospital and Research Centre · INSouthampton Children's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly recognition is crucial for occult spinal dysraphism associated with congenital spinal deformities. There is limited literature available on its occurrence in congenital scoliosis and kyphosis in the Indian population.

methodsOur study involved a retrospective review of 247 children who presented at a single centre. We analyzed their demographics and clinical and radiological findings, which included the type of deformity, its location, vertebral anomaly, Cobb angle, and MRI findings. The deformities were categorized as congenital scoliosis or congenital kyphosis with failure of formation, failure of segmentation, or both.

resultsA total of 247 cases were examined (congenital scoliosis-229, congenital kyphosis-18). The average age was seven years (range 0.8 to 19 years, SD 4.6). The mean Cobb angle at presentation in the congenital scoliosis group was 49.4° (range 8 to 145°, SD 23.77) for those with abnormal MRI and 42.45° (range 5 to 97°, SD 20.09) for those with normal MRI. For the congenital kyphosis group, the mean K angle at presentation was 47.7° (range 14 to 110°, SD 33.33) for those with abnormal MRI and 47.36° (range 15 to 70°, SD 16.63) for those with normal MRI. Abnormal MRI results were observed in 130 of the patients (congenital scoliosis-53.7%, congenital kyphosis-38.8%). The highest incidence of abnormal MRI findings was observed in the failure of segmentation (66.6%) and mixed (65%) types. Deformities in the dorsal region had the highest incidence (61.9%). The most common dysraphism instances were diastematomyelia and tethered cord. There was a significant correlation between type of deformity and presence of dysraphism.

conclusionThis is the largest case series of congenital scoliosis and kyphosis reported from India. We found a high incidence of occult spinal dysraphism as compared to other published series. Occult spinal dysraphism is more common in the thoracic region. Diastematomyelia followed by tethered cord was the most common anomaly observed. We recommend MRI screening of whole spine and craniovertebral junction.

Indexed as

KyphosisMagnetic Resonance ImagingScoliosisSpinal DysraphismAdolescentChildChild, PreschoolFemaleHumansIndiaInfantMaleRetrospective StudiesSpineYoung AdultCongenitalDeformityDysraphismKyphosisMRIOccultScoliosisSpine

Identifiers

PMID38581468
OpenAlexW4394011977

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.