Evidence map›Paper›PMID 38580760›Full record

ArticleDiscover oncology2024

Morbidity and mortality of patients with peritoneal malignancy following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Greta Hotza, Michael Karageorgos, Varvara Pastourmatzi, Nader Baniowda, Dimitrios Kyziridis, Apostolos Kalakonas, Nicolaos Chavouzis, Irene Hotza, Antonios-Apostolos Tentes

Open access · goldAbstract read
In one paragraph

Article in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Greta HotzaDepartment of Anesthesiology, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Michael KarageorgosIntensive Care Unit, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Varvara PastourmatziDepartment of Surgical Oncology, Peritoneal Surface Malignancy Program, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Nader BaniowdaIntensive Care Unit, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Dimitrios KyziridisDepartment of Surgical Oncology, Peritoneal Surface Malignancy Program, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Apostolos KalakonasDepartment of Anesthesiology, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Nicolaos ChavouzisIntensive Care Unit, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Irene HotzaDepartment of Anesthesiology, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece.
Antonios-Apostolos TentesDepartment of Surgical Oncology, Peritoneal Surface Malignancy Program, EUROMEDICA Kyanous Stavros, Viziis 1, 54636, Thessaloniki, Greece. tolistentes@gmail.com.
Kyanous Stavros Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to record the incidence, and identify the prognostic variables of morbidity and mortality in patients with peritoneal malignancy undergoing cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC).

methodsThe files of patients with peritoneal malignancy who underwent CRS + HIPEC from 2015-2022 were retrieved. Morbidity and hospital mortality were recorded and correlated to a variety of clinical variables.

resultsA total of 44/192 (22.9%) patients were recorded with postoperative complications. Grade 3 and 4 complications were 12.5%. The possible prognostic variables of morbidity were the extent of peritoneal malignancy and the number of suture lines. The mortality rate was 2.5% (5 patients). The number of FFP units, and peritonectomy procedures were identified as possible prognostic variables of hospital mortality.

conclusionsThe morbidity rate in patients undergoing CRS + HIPEC is acceptable compared to morbidity of previous publications or major gastrointestinal surgical operations. The possible prognostic variables of morbidity are the extent of peritoneal malignancy, and the number of suture lines. The mortality rate is low. The possible prognostic variables of mortality are the number of FFP units, and the number of peritonectomy procedures.

Indexed as

Cytoreductive surgeryHIPECIn-hospital mortalityMorbidity

Identifiers

PMID38580760
PMCPMC10997575
OpenAlexW4393999002

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.