Evidence map›Paper›PMID 38580428›Full record

ReviewThe Lancet. Planetary health2024

Interconnecting global threats: climate change, biodiversity loss, and infectious diseases.

Alaina Pfenning-Butterworth, Lauren B Buckley, John M Drake, Johannah E Farner, Maxwell J Farrell, Alyssa-Lois M Gehman, Erin A Mordecai, Patrick R Stephens, John L Gittleman, T Jonathan Davies

Abstract readReview
In one paragraph

Review in The Lancet. Planetary health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Climate-driven host ecology as a framework for zoonotic disease risk: Understanding transferability across arenavirus systems.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
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  7. Article
  8. Drivers of bat researchers' intent to adopt field hygiene practices.Conservation biology : the journal of the Society for Conservation Biology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Implementing the Kunming-Montreal Biodiversity Targets.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alaina Pfenning-ButterworthDepartment of Botany, University of British Columbia, Vancouver, BC, Canada. Electronic address: alaina.pfenning@botany.ubc.ca.
Lauren B BuckleyDepartment of Biology, University of Washington, Seattle, WA, USA.
John M DrakeSchool of Ecology, University of Georgia, Athens, GA, USA; Center for the Ecology of Infectious Diseases, University of Georgia, Athens, GA, USA.
Johannah E FarnerDepartment of Biology, Stanford University, Stanford, CA, USA.
Maxwell J FarrellDepartment of Ecology & Evolutionary Biology, University of Toronto, Toronto, ON, Canada; School of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.
Alyssa-Lois M GehmanInstitute for the Oceans and Fisheries, University of British Columbia, Vancouver, BC, Canada; Hakai Institute, Calvert, BC, Canada.
Erin A MordecaiDepartment of Biology, Stanford University, Stanford, CA, USA.
Patrick R StephensDepartment of Integrative Biology, Oklahoma State University, Stillwater, OK, USA.
John L GittlemanSchool of Ecology, University of Georgia, Athens, GA, USA; Nicholas School for the Environment, Duke University, Durham, NC, USA.
T Jonathan DaviesDepartment of Botany, University of British Columbia, Vancouver, BC, Canada; Department of Forest and Conservation Sciences, University of British Columbia, Vancouver, BC, Canada. Electronic address: j.davies@ubc.ca.

Funding

The child health impacts of overlapping vector-borne diseases in KenyaR01AI102918 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud · 2013 to 2026
$7.7M
Leveraging environmental drivers to predict vector-borne disease transmissionR35GM133439 · NIGMS · STANFORD UNIVERSITY · PI Erin Mordecai · 2019 to 2026
$3.2M
Modeling the influence of temperature on the evolution of vector-virus interactionsR01AI168097 · NIAID · WADSWORTH CENTER · PI Alexander Timothy Ciota · 2022 to 2026
$2.4M
Spillover of Ebola and other filoviruses at ecological boundariesR01AI156866 · NIAID · UNIVERSITY OF GEORGIA · PI STEPHENS, PATRICK · 2020 to 2024
$2.2M
NIAID NIH HHS R01 AI102918NIAID NIH HHS R01 AI156866NIAID NIH HHS R01 AI168097NIGMS NIH HHS R35 GM133439
6 · The paper itself

Abstract

The concurrent pressures of rising global temperatures, rates and incidence of species decline, and emergence of infectious diseases represent an unprecedented planetary crisis. Intergovernmental reports have drawn focus to the escalating climate and biodiversity crises and the connections between them, but interactions among all three pressures have been largely overlooked. Non-linearities and dampening and reinforcing interactions among pressures make considering interconnections essential to anticipating planetary challenges. In this Review, we define and exemplify the causal pathways that link the three global pressures of climate change, biodiversity loss, and infectious disease. A literature assessment and case studies show that the mechanisms between certain pairs of pressures are better understood than others and that the full triad of interactions is rarely considered. Although challenges to evaluating these interactions-including a mismatch in scales, data availability, and methods-are substantial, current approaches would benefit from expanding scientific cultures to embrace interdisciplinarity and from integrating animal, human, and environmental perspectives. Considering the full suite of connections would be transformative for planetary health by identifying potential for co-benefits and mutually beneficial scenarios, and highlighting where a narrow focus on solutions to one pressure might aggravate another.

Indexed as

Communicable DiseasesEcosystemAnimalsBiodiversityClimate ChangeHumansModels, Theoretical

Identifiers

PMID38580428
PMCPMC11090248

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.