Evidence map›Paper›PMID 38580348›Full record

SynthesisRMD open2024

Recommendations for physical activity and exercise in persons living with Systemic Lupus Erythematosus (SLE): consensus by an international task force.

Julien Blaess, Sophie Geneton, Thibaut Goepfert, Simone Appenzeller, Gabriel Bordier, Thomas Davergne, Yurilis Fuentes, Håvard Haglo, Karen Hambly, Dominique Kinnett-Hopkins and 12 more

Registry-linked trialOpen access · goldAbstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07716462 (Exercise and Muscle Biology in Systemic Lupus Erythematosus), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07716462 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Exercise and Muscle Biology in Systemic Lupus Erythematosus

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2026 to 2027Enrolled20ConditionsSystemic Lupus Erthematosus, Fatigue, Exercise TrainingArmsPersonalized Home-Based High-Intensity Interval Training
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
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  9. Article
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  12. Review
  13. Towards precision medicine for systemic lupus erythematosus and neuropsychiatric manifestations.Expert review of precision medicine and drug development · 2025
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 20 institutions in 15 countries.

Julien BlaessDepartment of Physiology and Functional Exploration, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Sophie GenetonDepartment of Rheumatology, National Reference Center for Rare Autoimmune Diseases (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Thibaut GoepfertDepartment of Rheumatology, National Reference Center for Rare Autoimmune Diseases (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Simone AppenzellerSchool of Medical Science, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
Gabriel BordierService de rhumatologie, CHU d'Angers, Angers, France.
Thomas DavergneSchool of physiotherapy Boris Dolto, DUS2R, University of Paris Cité, Paris, France.ORCID 0000-0001-7869-0062
Yurilis FuentesDepartamento de Medicina, Universidad de Oriente, Ciudad Bolívar, Venezuela.
Håvard HagloTreningsklinikken, Medical Rehabilitation Clinic, Trondheim, Norway.ORCID 0000-0001-7147-4463
Karen HamblySchool of Sport and Exercise Sciences, University of Kent, Canterbury, UK.
Dominique Kinnett-HopkinsSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
Kuei-Ying SuDivision of Allergy,Immunology and Rheumatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Alexandra LeggeDivision of Rheumatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Linda LiArthritis Research Canada, Vancouver, British Columbia, Canada.
Anselm MakDivision of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ivan PadjenSchool of Medicine, Division of Clinical Immunology and Rheumatology, National Referral Centre for SLE and Related Disorders, University of Zagreb, Zagreb, Croatia.
Savino SciasciaUniversity Center of Excellence on Nephrological, Rheumatological and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) including Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley (North-West Italy), San Giovanni Bosco Hub Hospital, ASL Città di Torino and Department of Clinical and Biological Sciences of the University of Turin, Turin, Italy.
Saira Z SheikhDepartment of Medicine, Division of Rheumatology, Allergy & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-4128-0443
Alberto Soriano-MaldonadoDepartment of Education, Faculty of Education Sciences, and SPORT Research Group (CTS-1024), CIBIS (Centro de Investigación para el Bienestar y la Inclusión Social) Research Center, University of Almería, Almería, Spain.ORCID 0000-0002-4626-420X
Manuel F Ugarte-GilGrupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Cientifica del Sur, Lima Peru and Rheumatology Department, Hospital Guillermo Almenara Irigoyen - EsSalud, Lima, Peru.
Md Yuzaiful Md YusofLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID 0000-0003-3131-9121
Ioannis ParodisDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-4875-5395
Laurent ArnaudDepartment of Rheumatology, National Reference Center for Rare Autoimmune Diseases (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, France laurent.arnaud@chru-strasbourg.fr.ORCID 0000-0002-8077-8394
Hôpitaux Universitaires de Strasbourg · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire de Martinique · MQDalhousie University · CAKarolinska University Hospital · SENational University of Singapore · SGOspedale San Giovanni Bosco · ITSmerteklinikken · NOTzu Chi University · TWUniversidad Científica del Sur · PEUniversidad de Oriente · VEUniversidade Estadual de Campinas (UNICAMP) · BRUniversité Paris Cité · FRUniversity Hospital Centre Zagreb · HRUniversity of Almería · ESUniversity of British Columbia · CAUniversity of Kent · GBUniversity of Leeds · GBUniversity of Michigan · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis international task force aimed to provide healthcare professionals and persons living with systemic lupus erythematosus (SLE) with consensus-based recommendations for physical activity and exercise in SLE.

methodsBased on evidence from a systematic literature review and expert opinion, 3 overarching principles and 15 recommendations were agreed on by Delphi consensus.

resultsThe overarching principles highlight the importance of shared decision-making and the need to explain the benefits of physical activity to persons living with SLE and other healthcare providers. The 15 specific recommendations state that physical activity is generally recommended for all people with SLE, but in some instances, a medical evaluation may be needed to rule out contraindications. Pertaining to outdoor activity, photoprotection is necessary. Both aerobic and resistance training programmes are recommended, with a gradual increase in frequency and intensity, which should be adapted for each individual, and ideally supervised by qualified professionals.

conclusionIn summary, the consensus reached by the international task force provides a valuable framework for the integration of physical activity and exercise into the management of SLE, offering a tailored evidence-based and eminence-based approach to enhance the well-being of individuals living with this challenging autoimmune condition.

Indexed as

Advisory CommitteesExerciseLupus Erythematosus, SystemicDelphi TechniqueExercise TherapyHumansautoimmune diseaseslupus erythematosus, systemicsystemic lupus erythematosus

Identifiers

PMID38580348
PMCPMC11002419
OpenAlexW4393989427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.