Evidence map›Paper›PMID 38580317›Full record

ReviewJournal of medicinal chemistry2024

Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death.

Ganga Reddy Velma, Isabella S Krider, Erick T M Alves, Jenna M Courey, Megan S Laham, Gregory R J Thatcher

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ganga Reddy VelmaDepartment of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-5054-2519
Isabella S KriderDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0009-0005-6444-7834
Erick T M AlvesDepartment of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Jenna M CoureyDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Megan S LahamDepartment of Chemistry & Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Gregory R J ThatcherDepartment of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
University of Arizona · US

Funding

CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
Novel allosteric activation of nicotinamide rescueRF1AG067771 · NIA · UNIVERSITY OF ARIZONA · PI THATCHER, GREGORY R. J · 2020 to 2020
$2.3M
NIA NIH HHS RF1 AG067771NIGMS NIH HHS T32 GM008804
6 · The paper itself

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the rate-limiting step in NAD

Indexed as

Enzyme InhibitorsNicotinamide PhosphoribosyltransferaseAllosteric RegulationAnimalsAntineoplastic AgentsCell DeathCytokinesHumansNADNeoplasmsAntineoplastic AgentsCytokinesEnzyme InhibitorsNADNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, human

Identifiers

PMID38580317
PMCPMC11056997
OpenAlexW4393969637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.