Evidence map›Paper›PMID 38579901›Full record

ReviewNeuroscience and biobehavioral reviews2024

GABA system as the cause and effect in early development.

Irina Topchiy, Julie Mohbat, Oluwarotimi O Folorunso, Ziyi Zephyr Wang, Cayetana Lazcano-Etchebarne, Elif Engin

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. GABAFrontiers in pharmacology · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Irina TopchiyDivision of Basic Neuroscience, McLean Hospital, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.
Julie MohbatDivision of Basic Neuroscience, McLean Hospital, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA; School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Lausanne CH-1015, Switzerland.
Oluwarotimi O FolorunsoDivision of Basic Neuroscience, McLean Hospital, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.
Ziyi Zephyr WangDivision of Basic Neuroscience, McLean Hospital, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA.
Cayetana Lazcano-EtchebarnePonce Health Sciences University School of Medicine, Ponce 00732, Puerto Rico.
Elif EnginDivision of Basic Neuroscience, McLean Hospital, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, Boston, MA 02215, USA. Electronic address: eengin@mclean.harvard.edu.
Harvard University · USMcLean Hospital · USPonce Health Sciences University · PR

Funding

Disruptions in the brain reward system through postnatal exposure to GABA agonists and anestheticsR01HD104656 · NICHD · MCLEAN HOSPITAL · PI ENGIN, ELIF · 2022 to 2025
$1.8M
NICHD NIH HHS R01 HD104656
6 · The paper itself

Abstract

GABA is the primary inhibitory neurotransmitter in the adult brain and through its actions on GABA

Indexed as

Braingamma-Aminobutyric AcidAnimalsGABAergic NeuronsHumansReceptors, GABA-Agamma-Aminobutyric AcidReceptors, GABA-AEarly developmentEarly life stressFetal alcohol syndromeGABAGABAA receptorsMaternal immune activation

Identifiers

PMID38579901
PMCPMC11081854
OpenAlexW4393945228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.