Evidence map›Paper›PMID 38579698›Full record

ArticleThe American journal of tropical medicine and hygiene2024

High Efficacy of Ivermectin for Strongyloidiasis Treatment.

Chatchawan Sengthong, Somchai Pinlaor, Manachai Yingklang, Ornuma Haonon, Chanakan Jantawong, Porntip Pinlaor, Paiboon Sithithaworn, Nuttanan Hongsrichan

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Ivermectin Treatment for Strongyloidiasis in Thailand.The American journal of tropical medicine and hygiene · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Chatchawan SengthongThe Office of Disease Prevention and Control 7, Khon Kaen, Thailand.
Somchai PinlaorDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Manachai YingklangDepartment of Fundamentals of Public Health, Faculty of Public Health, Burapha University, Chonburi, Thailand.
Ornuma HaononCellular and Molecular Immunology Research Unit, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand.
Chanakan JantawongDepartment of Medical Technology, Faculty of Allied Health Science, Nakhonratchasima College, Nakhon Ratchasima, Thailand.
Porntip PinlaorChronic Kidney Disease Prevention in The Northeast of Thailand, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Paiboon SithithawornDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Nuttanan HongsrichanDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Khon Kaen University · THBurapha University · THMaharat Nakhon Ratchasima Hospital · THNaresuan University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with Strongyloides stercoralis is often asymptomatic but can be life-threatening in immunocompromised patients, which can be prevented by ivermectin (IVM) treatment. The efficacy of IVM has been reported to have lessened over time in some regions as a consequence of prolonged use and mass treatment campaigns. Ivermectin has been used in Thailand for more than a decade; therefore, we investigated the efficacy of a single dose (200 µg/kg) of IVM against in asymptomatic strongyloidiasis in northeastern Thailand. Fecal samples were collected before and 2 weeks after treatment and were analyzed for the presence of Strongyloides using a modified agar plate culture and the formalin-ethyl acetate concentration technique. Our results showed that single-dose IVM treatment successfully eliminated S. stercoralis infection in asymptomatic individuals in the endemic area with a 100% cure rate, indicating the high efficacy of IVM treatment in strongyloidiasis in northeast Thailand.

Indexed as

FecesIvermectinStrongyloides stercoralisStrongyloidiasisAdolescentAdultAnimalsAntiparasitic AgentsFemaleHumansMaleMiddle AgedThailandTreatment OutcomeYoung AdultAntiparasitic AgentsIvermectin

Identifiers

PMID38579698
PMCPMC11066358
OpenAlexW4393410635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.