Evidence map›Paper›PMID 38579014›Full record

ArticleScience immunology2024

Regulation of BCR-mediated Ca

Lingling Zhang, Amparo Toboso-Navasa, Arief Gunawan, Abdouramane Camara, Rinako Nakagawa, Katja Finsterbusch, Probir Chakravarty, Rebecca Newman, Yang Zhang, Martin Eilers and 4 more

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. HemaSphere · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Lingling ZhangImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0001-7423-3761
Amparo Toboso-NavasaImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0001-8560-1507
Arief GunawanImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0002-4136-3620
Abdouramane CamaraImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0003-1521-4821
Rinako NakagawaImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0003-2511-0444
Katja FinsterbuschImmunoregulation, Francis Crick Institute, London, UK.
Probir ChakravartyBioinformatics and Biostatistics, Francis Crick Institute, London, UK.ORCID 0000-0003-1146-8824
Rebecca NewmanImmune Receptor Activation Laboratory, Francis Crick Institute, London, UK.
Yang ZhangInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Martin EilersTheodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany.
Andreas WackImmunoregulation, Francis Crick Institute, London, UK.ORCID 0000-0001-5226-2991
Pavel TolarImmune Receptor Activation Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0003-4693-7299
Kai-Michael ToellnerInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.ORCID 0000-0001-8404-645X
Dinis Pedro CaladoImmunity and Cancer, Francis Crick Institute, London, UK.ORCID 0000-0001-8239-7184
The Francis Crick Institute · GBUniversity of Birmingham · GBUniversity of Würzburg · DE

Funding

Cancer Research UK CC2078Medical Research Council CC2006Medical Research Council CC2085
6 · The paper itself

Abstract

The transition from immunoglobulin M (IgM) to affinity-matured IgG antibodies is vital for effective humoral immunity. This is facilitated by germinal centers (GCs) through affinity maturation and preferential maintenance of IgG

Indexed as

B-LymphocytesImmunoglobulin GMembrane ProteinsAnimalsGerminal CenterImmunoglobulin MMiceProtein Inhibitors of Activated STATSignal TransductionUbiquitin-Protein LigasesImmunoglobulin GImmunoglobulin MMembrane ProteinsMiz1 protein, mouseProtein Inhibitors of Activated STATUbiquitin-Protein Ligases

Identifiers

PMID38579014
PMCPMC7615907
OpenAlexW4393998921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.