Evidence map›Paper›PMID 38578781›Full record

ArticlePloS one2024

Does radiofrequency ablation procedural data improve the accuracy of identifying atrial fibrillation recurrence?

Mingkai Peng, Amit Doshi, Yariv Amos, Liat Tsoref, Mati Amit, Don Yungher, Rahul Khanna, Paul M Coplan

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mingkai PengEpidemiology & Real-World Data Sciences, MedTech, Johnson & Johnson, New Brunswick, New Jersey, United States of America.
Amit DoshiMercy Hospital, St. Louis, Missouri, United States of America.
Yariv AmosBiosense Webster LTD, Haifa Technology Center, Haifa, Israel.
Liat TsorefBiosense Webster LTD, Haifa Technology Center, Haifa, Israel.
Mati AmitBiosense Webster LTD, Haifa Technology Center, Haifa, Israel.
Don YungherBiosense Webster LTD, Haifa Technology Center, Haifa, Israel.
Rahul KhannaEpidemiology & Real-World Data Sciences, MedTech, Johnson & Johnson, New Brunswick, New Jersey, United States of America.
Paul M CoplanEpidemiology & Real-World Data Sciences, MedTech, Johnson & Johnson, New Brunswick, New Jersey, United States of America.ORCID 0000-0002-7078-7780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiofrequency ablation (RFA) using the CARTO 3D mapping system is a common approach for pulmonary vein isolation to treat atrial fibrillation (AF). Linkage between CARTO procedural data and patients' electronical health records (EHR) provides an opportunity to identify the ablation-related parameters that would predict AF recurrence. The objective of this study is to assess the incremental accuracy of RFA procedural data to predict post-ablation AF recurrence using machine learning model. Procedural data generated during RFA procedure were downloaded from CARTONET and linked to deidentified Mercy Health EHR data. Data were divided into train (70%) and test (30%) data for model development and validation. Automate machine learning (AutoML) was used to predict 1 year AF recurrence, defined as a composite of repeat ablation, electrical cardioversion, and AF hospitalization. At first, AutoML model only included Patients' demographic and clinical characteristics. Second, an AutoML model with procedural variables and demographical/clinical variables was developed. Area under receiver operating characteristic curve (AUROC) and net reclassification improvement (NRI) were used to compare model performances using test data. Among 306 patients, 67 (21.9%) patients experienced 1-year AF recurrence. AUROC increased from 0.66 to 0.78 after adding procedural data in the AutoML model based on test data. For patients with AF recurrence, NRI was 32% for model with procedural data. Nine of 10 important predictive features were CARTO procedural data. From CARTO procedural data, patients with lower contact force in right inferior site, long ablation duration, and low number of left inferior and right roof lesions had a higher risk of AF recurrence. Patients with persistent AF were more likely to have AF recurrence. The machine learning model with procedural data better predicted 1-year AF recurrence than the model without procedural data. The model could be used for identification of patients with high risk of AF recurrence post ablation.

Indexed as

Ablation TechniquesAtrial FibrillationCatheter AblationPulmonary VeinsRadiofrequency AblationHumansRecurrenceTime FactorsTreatment Outcome

Identifiers

PMID38578781
PMCPMC10997092

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.