Evidence map›Paper›PMID 38578599›Full record

ArticleSpine deformity2024

Three-dimensional vertebral shape changes confirm growth modulation after anterior vertebral body tethering for idiopathic scoliosis.

Joshua N Speirs, Stefan Parent, Michael Kelly, Vidyadhar V Upasani, Maty Petcharaporn, Tracey P Bryan, Peter O Newton

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Spine deformity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Joshua N SpeirsDepartment of Orthopedics, University of Utah, Salt Lake City, UT, USA.
Stefan ParentDepartment of Orthopaedics, CHU Sainte-Justine, Montreal, QC, Canada.
Michael KellyDivision of Orthopedics and Scoliosis, Rady Children's Hospital, 3020 Children's Way, San Diego, CA, 92123, USA.
Vidyadhar V UpasaniDivision of Orthopedics and Scoliosis, Rady Children's Hospital, 3020 Children's Way, San Diego, CA, 92123, USA.
Maty PetcharapornSetting Scoliosis Straight Foundation, San Diego, CA, USA.
Tracey P BryanDivision of Orthopedics and Scoliosis, Rady Children's Hospital, 3020 Children's Way, San Diego, CA, 92123, USA.
Peter O NewtonDivision of Orthopedics and Scoliosis, Rady Children's Hospital, 3020 Children's Way, San Diego, CA, 92123, USA. pnewton.rady@gmail.com.ORCID 0000-0001-9437-7973
University of California San Diego · USCentre Hospitalier Universitaire Sainte-Justine · CARady Children's Hospital-San Diego · USSetting Scoliosis Straight Foundation · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate three-dimensional (3D) vertebra and disk shape changes over 2 years following anterior vertebral body tether (AVBT) placement in patients with idiopathic scoliosis (IS).

methodsPatients with right thoracic IS treated with AVBT were retrospectively evaluated. 3D reconstructions were created from biplanar radiographs. Vertebral body and disk height (anterior, posterior, left and right) and shape (wedging angle) were recorded over the three apical segments in the local vertebral reference planes. Changes in height and wedging were measured through 2 years postoperatively. Change in patient height was correlated with changes in the spine dimensions.

resultsForty-nine patients (Risser 0-3, Sanders 2-4) were included. The mean age was 12.2 ± 1.4 years (range 8-14). The mean coronal curve was 51 ± 10° preoperatively, 31 ± 9° at first postoperative time point and 27 ± 11° at 2-year follow-up (p < 0.001). The mean patient height increased 8 cm by 2 years (p < 0.001). The left side of the spine (vertebra + disc) grew in height by 2.2 mm/level versus 0.7 mm/level on the right side (p < 0.001). This differential growth was composed of 0.5 mm/vertebral level and 1.0 mm/disk level. Evaluation of the change in disk heights showed significantly decreased height anteriorly (- 0.4 mm), posteriorly (- 0.3 mm) and on the right (- 0.5 mm) from FE to 2 years. Coronal wedging reduced 2.3°/level with 1.1°/vertebral level change and 1.2°/disk level. There was no differential growth in the sagittal plane (anterior/posterior height). Patient height change moderately correlated with 3D measures of vertebra + disk shape changes.

conclusionsThree-dimensional analysis confirms AVBT in skeletally immature patients results in asymmetric growth of the apical spine segments. The left (untethered) side length increased more than 3 × than the right (tethered) side length with differential effects observed within the vertebral bodies and disks, each correlating with overall patient height change.

Indexed as

Intervertebral DiscScoliosisThoracic VertebraeVertebral BodyAdolescentChildHumansImaging, Three-DimensionalRetrospective StudiesTreatment OutcomeAnterior vertebral body tetherDiskGrowth modulationIdiopathic scoliosisThree-dimensionalVertebra

Identifiers

PMID38578599
OpenAlexW4393993654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.