Evidence map›Paper›PMID 38578598›Full record

ArticleSpine deformity2024

Biomechanical analysis of a trans-discal, multi-level stabilization screw (MLSS) at the upper instrumented vertebra (UIV) of long posterior thoracolumbar instrumentations.

Andrew P Collins, Anoli A Shah, Niloufar Shekouhi, Vijay K Goel, Alekos A Theologis

Open access · hybridAbstract read
In one paragraph

Article in Spine deformity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew P CollinsDepartment of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, USA.
Anoli A ShahEngineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Surgery, Colleges of Engineering and Medicine, University of Toledo, Toledo, OH, USA.
Niloufar ShekouhiEngineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Surgery, Colleges of Engineering and Medicine, University of Toledo, Toledo, OH, USA.
Vijay K GoelEngineering Center for Orthopaedic Research Excellence (E-CORE), Departments of Bioengineering and Surgery, Colleges of Engineering and Medicine, University of Toledo, Toledo, OH, USA.
Alekos A TheologisDepartment of Orthopaedic Surgery, San Francisco (UCSF), University of California, 500 Parnassus Ave, MUW 3rd Floor, San Francisco, CA, USA. alekos.theologis@ucsf.edu.ORCID 0000-0001-6170-2813
University of Toledo · USUniversity of California, San Francisco · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate proximal junctional biomechanics of a MLSS relative to traditional pedicle screw fixation at the proximal extent of T10-pelvis posterior instrumentation constructs (T10-p PSF).

methodsA previously validated three-dimensional osseoligamentous spinopelvic finite element (FE) model was used to compare proximal junctional range-of-motion (ROM), vertebral body stresses, and discal biomechanics between two groups: (1) T10-p with a T10-11 MLSS ("T10-11 MLSS") and (2) T10-p with a traditional T10 pedicle screw ("Traditional T10-PS").

resultsThe T10-11 MLSS had a 5% decrease in T9 cortical bone stress compared to Traditional T10-PS. Conversely, the T10 and T11 bone stresses increased by 46% and 98%, respectively, with T10-11 MLSS compared to Traditional T10-PS. Annular stresses and intradiscal pressures (IDP) were similar at T9-T10 between constructs. At the T10-11 disc, T10-11 MLSS decreased annular stresses by 29% and IDP by 48% compared to Traditional T10-PS. Adjacent ROM (T8-9 & T9-10) were similar between T10-11 MLSS and Traditional T10-PS. T10-11 MLSS had 39% greater ROM at T10-11 and 23% less ROM at T11-12 compared to Traditional T10-PS.

conclusionsIn this FE analysis, a T10-11 MLSS at the proximal extent of T10-pelvis posterior instrumentation resulted in increased T10 and T11 cortical bone stresses, decreased discal annular stress and IDP and increased ROM at T10-11, and no change in ROM at the adjacent level. Given the complex and multifactorial nature of proximal junctional kyphosis, these results require additional biomechanical and clinical evaluations to determine the clinical utility of MLSS on the proximal junctions of thoracolumbar posterior instrumented fusions.

Indexed as

Finite Element AnalysisLumbar VertebraePedicle ScrewsRange of Motion, ArticularSpinal FusionThoracic VertebraeBiomechanical PhenomenaBone ScrewsHumansIntervertebral DiscStress, MechanicalAdjacent segmentBiomechanicsFinite element analysisMulti-level stabilizing screwTrans-discal screws

Identifiers

PMID38578598
PMCPMC11217123
OpenAlexW4393990892

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.