ArticleWorld journal of pediatrics : WJP2024
Prospective cohort study on facial profile changes in infants with Robin sequence and healthy controls.
Article in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Robin Sequence: From Dilemmas to Developing an Adaptable Standardized Stepwise Approach.Acta paediatrica (Oslo, Norway : 1992) · 2025Pooled it
- Orthodontic Airway Plate Therapy for Infants with Robin Sequence: Clinical Principles, Current Evidence, and Evolving Innovations.Neonatology · 2026Review
- Morphometric Findings in Adolescents with Robin Sequence: A Photographic and Cephalometric Study of the Face and Mandible.Children (Basel, Switzerland) · 2026Article
- Complete Protocol and Guidelines for the Implementation and Manufacturing of the Tübingen Palatal Plate-An Interdisciplinary Technical Note on the Tübingen Approach for Infants with Robin Sequence.Bioengineering (Basel, Switzerland) · 2025Article
- Orthodontic Perspectives in the Interdisciplinary Management of Pediatric Obstructive Sleep Apnea.Children (Basel, Switzerland) · 2025Review
- Palatal plates for treating infants with Robin sequence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Article
- Why are we not working to prevent OSA?Sleep · 2024Article
- Diagnosis and Early Management of Robin Sequence.Children (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundVarious conservative and surgical approaches exist to treat Robin sequence (RS), but their effects on facial profile and mandibular catch-up growth are unclear. A functional treatment concept, used in our centre for 25 years, includes an individualized palatal plate with a velo-pharyngeal extension and intensive feeding training.
methodsWe performed a prospective study to objectively describe facial profiles in infants with RS treated with the above concept. Infants with isolated RS were admitted to our tertiary perinatal and national referral centre for craniofacial malformations between May 2018 and Nov 2019. Infants with RS received 3D-photographs during clinically indicated visits. Healthy controls were recruited from Dec 2018 to Sep 2019 and received 3D-photographs every 3 months. The digitally measured jaw index (JI), defined as alveolar overjet (O) x maxillary arch (U)/mandibular arch (L), and the soft tissue reference points A'-point, Nasion', B'-point angle (ANB'), describing the relative position of maxilla to mandible, were evaluated. Linear mixed models were used to examine time trajectories in JI and ANB'.
resultsA total of 207 3D images, obtained in 19 infants with RS and 32 controls, were analysed. JI and ANB' decreased over time in both groups [for JI - 0.18 (95% CI - 0.25 to - 0.10); for ANB': - 0.40° per month [(95% CI - 0.48 to - 0.32)]] but remained lower in controls [for JI - 2.5 (95% CI - 3.2 to - 1.8); for ANB'-1.7° (95% CI - 2.4 to - 1.0)]. Also, the ANB' model showed a significant effect of the interaction term diagnosis x age.
conclusionsBased on longitudinal 3D images, we describe changes in objective parameters of facial profile in infants with and without RS during the first year of life. Our findings indicate catch-up growth in infants treated for RS. Video Abstract.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.