ArticleInsights into imaging2024
Impact of CT-determined low kidney volume on renal function decline: a propensity score-matched analysis.
Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- A z-score-based reference system for renal volume using three-dimensional ultrasound: from model to clinical tool.Quantitative imaging in medicine and surgery · 2026Article
- Nationwide organ volume distributions and cross-sectional age-associated differences in abdominal CT from Japan.Japanese journal of radiology · 2026Article
- Can radiomics-based innovations improve the diagnosis of kidney fibrosis in diabetic nephropathy?Clinical kidney journal · 2026Review
- Intra-Individual Reproducibility of Automated Abdominal Organ Segmentation-Performance of TotalSegmentator Compared to Human Readers and an Independent nnU-Net Model.Journal of imaging informatics in medicine · 2025Article
- Usefulness of Radiomics and Kidney Volume Based on Non-Enhanced Computed Tomography in Chronic Kidney Disease: Initial Report.Kidney & blood pressure research · 2025Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo investigate the relationship between low kidney volume and subsequent estimated glomerular filtration rate (eGFR) decline in eGFR category G2 (60-89 mL/min/1.73 m
methodsIn this retrospective study, we evaluated 5531 individuals with eGFR category G2 who underwent medical checkups at our institution between November 2006 and October 2017. Exclusion criteria were absent for follow-up visit, missing data, prior renal surgery, current renal disease under treatment, large renal masses, and horseshoe kidney. We developed a 3D U-net-based automated system for renal volumetry on CT images. Participants were grouped by sex-specific kidney volume deviations set at mean minus one standard deviation. After 1:1 propensity score matching, we obtained 397 pairs of individuals in the low kidney volume (LKV) and control groups. The primary endpoint was progression of eGFR categories within 5 years, assessed using Cox regression analysis.
resultsThis study included 3220 individuals (mean age, 60.0 ± 9.7 years; men, n = 2209). The kidney volume was 404.6 ± 67.1 and 376.8 ± 68.0 cm
conclusionLow kidney volume may adversely affect subsequent eGFR maintenance; hence, the use of imaging metrics may help predict eGFR decline. CRITICAL RELEVANCE STATEMENT: Low kidney volume is a significant predictor of reduced kidney function over time; thus, kidney volume measurements could aid in early identification of individuals at risk for declining kidney health. KEY POINTS: • This study explores how kidney volume affects subsequent kidney function maintenance. • Low kidney volume was associated with estimated glomerular filtration rate decreases. • Low kidney volume is a prognostic indicator of estimated glomerular filtration rate decline.
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