Evidence map›Paper›PMID 38578522›Full record

SynthesisObesity surgery2024

Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis.

Tannaz Jamialahamdi, Ali H Eid, Ninh T Nguyen, Kishore M Gadde, Vasily N Sukhorukov, Wael Almahmeed, Matthew Kroh, Amirhossein Sahebkar

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Tannaz Jamialahamdi *Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali H Eid *Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Ninh T NguyenDepartment of Surgery, University of California Irvine Medical Center, Orange, CA, USA.
Kishore M GaddeDepartment of Surgery, University of California Irvine Medical Center, Orange, CA, USA.
Vasily N SukhorukovInstitute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, Moscow, 125315, Russia.
Wael AlmahmeedHeart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Matthew KrohDigestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Amirhossein SahebkarCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. amir_saheb2000@yahoo.com.ORCID 0000-0002-8656-1444
Mashhad University of Medical Sciences · IRUniversity of California, Irvine Medical Center · USCleveland Clinic · USQatar University · QAResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review was performed using Embase, Google Scholar, PubMed, Scopus, and Web of Science. The meta-analysis was provided by Comprehensive Meta-Analysis (CMA) V4 software. The overall effect size was detected by a random-effects meta-analysis and the leave-one-out approach. Random-effects meta-analysis of 7 studies including 191 subjects showed a significant reduction in CD40L after bariatric surgery (standardized mean difference (SMD), - 0.531; 95% CI, - 0.981, - 0.082; p = 0.021; I

Indexed as

Bariatric SurgeryCardiovascular DiseasesObesity, MorbidCD40 LigandHeart Disease Risk FactorsHumansRisk FactorsCD40 LigandCD40LImmune systemInflammationMetabolic bariatric surgeryWeight loss

Identifiers

PMID38578522
OpenAlexW4393993717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.