Evidence map›Paper›PMID 38578316›Full record

ArticleClinical and experimental medicine2024

Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis.

Yanli Jin, Fangyuan Wang, Jiale Tang, Liying Luo, Lingyu Huang, Fangyu Zhou, Enyu Qi, Xinyue Hu, Shuanglinzi Deng, Huan Ge and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yanli JinDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China.
Fangyuan WangDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China.
Jiale TangCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Liying LuoCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Lingyu HuangDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China.
Fangyu ZhouDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China.
Enyu QiDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China.
Xinyue HuCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Shuanglinzi DengCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Huan GeCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Yuanyuan JiangDepartment of Laboratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Juntao FengCenter of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.
Xiaozhao LiDepartment of Nephrology, Xiangya Hospital, Central South University, No.87 Xiangya Road, Kaifu District, Changsha, Hunan, China. lixiaozhao@csu.edu.cn.
Central South University · CNXiangya Hospital Central South University · CN

Funding

the Hunan Provincial Natural Science Foundation of China No. 2020JJ4887, No. 2023JJ30904
6 · The paper itself

Abstract

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blood vessels. There is increasing evidence that platelets play a crucial role not only in hemostasis but also in inflammation and innate immunity. In this study, we explored the relationship between platelet count, clinical characteristics, and the prognosis of patients with AAV. We divided 187 patients into two groups based on their platelet count. Clinicopathological data and prognostic information were retrospectively gathered from medical records. Univariate and multivariate regression analyses were used to identify risk factors for prognosis, including end-stage renal disease (ESRD) and mortality. The cutoff point for platelet count was set at 264.5 × 10

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisKidney Failure, ChronicHumansInflammationKidneyPlatelet CountPrognosisRetrospective StudiesSeverity of Illness IndexAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitisEnd-stage renal diseasePlatelet countPrognosisSurvival

Identifiers

PMID38578316
PMCPMC10997538
OpenAlexW4393994615

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.