ArticleImmunity, inflammation and disease2024
Coexistence of ankylosing spondylitis and Behçet's disease: Successful treatment with upadacitinib.
Article in Immunity, inflammation and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Successful upadacitinib treatment in anti-TNF-refractory intestinal Behçet's disease: a case report and literature review.Frontiers in medicine · 2026Article
- Upadacitinib for refractory Behçet's disease with myelodysplastic syndrome and trisomy 8/9: a case report and mechanistic insights.Frontiers in immunology · 2025Article
- New and future perspectives in Behçet's syndrome.Archives of rheumatology · 2024Review
- Review
- Coexistence of ankylosing spondylitis and Behçet's disease: Successful treatment with upadacitinib.Immunity, inflammation and disease · 2024Article
- Case report: Successful remission with upadacitinib in a young patient with anti-TNF-refractory intestinal Behçet's disease.Frontiers in immunology · 2024Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnkylosing spondylitis (AS) and Behçet's disease (BD) are distinct inflammatory disorders, but their coexistence is a rare clinical entity. This case sheds light on managing this complex scenario with Janus kinase (JAK) inhibitors. CASE PRESENTATION: A 42-year-old woman presented with a decade-long history of lower back pain, nocturnal spinal discomfort, recurrent eye issues, oral and genital ulcers, hearing loss, pus formation in the left eye, and abdominal pain. Multidisciplinary consultations and diagnostic tests confirmed AS (HLA-B27 positivity and sacroiliitis) and BD (HLA-B51). Elevated acute-phase markers were observed.
conclusionThis case fulfills diagnostic criteria for both AS and BD, emphasizing their coexistence. Notably, treatment with upadacitinib exhibited promising efficacy, underscoring its potential as a therapeutic option in patients with contraindications for conventional treatments. Our findings illuminate the intricate management of patients presenting with these two diverse systemic conditions and advocate for further exploration of JAK inhibitors in similar cases.
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