Evidence map›Paper›PMID 38577633›Full record

ArticleMethodology : European journal of research methods for the behavioral & social sciences2024

Bayesian profile regression for clustering analysis involving a longitudinal response and explanatory variables.

Anaïs Rouanet, Rob Johnson, Magdalena Strauss, Sylvia Richardson, Brian D Tom, Simon R White, Paul D W Kirk

Open access · hybridAbstract read
In one paragraph

Article in Methodology : European journal of research methods for the behavioral & social sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Multimorbidity Profiles and Severe In-Hospital Outcomes in Adults With Respiratory Syncytial Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anaïs RouanetMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Rob JohnsonMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Magdalena StraussMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Sylvia RichardsonMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Brian D TomMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Simon R WhiteMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
Paul D W KirkMRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, U.K.
University of Cambridge · GBEuropean Bioinformatics Institute · GB

Funding

Department of Health IS-BRC-1215-20014Medical Research Council MC_UU_00002/1Medical Research Council MC_UU_00002/10Medical Research Council MC_UU_00002/2Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

The identification of sets of co-regulated genes that share a common function is a key question of modern genomics. Bayesian profile regression is a semi-supervised mixture modelling approach that makes use of a response to guide inference toward relevant clusterings. Previous applications of profile regression have considered univariate continuous, categorical, and count outcomes. In this work, we extend Bayesian profile regression to cases where the outcome is longitudinal (or multivariate continuous) and provide PReMiuMlongi, an updated version of PReMiuM, the R package for profile regression. We consider multivariate normal and Gaussian process regression response models and provide proof of principle applications to four simulation studies. The model is applied on budding yeast data to identify groups of genes co-regulated during the

Identifiers

PMID38577633
PMCPMC7615733
OpenAlexW3213270548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.