Evidence map›Paper›PMID 38577322›Full record

ArticleNanotheranostics2024

Ultrasound enhanced siRNA delivery using cationic liposome-microbubble complexes for the treatment of squamous cell carcinoma.

Bin Qin, Xucai Chen, Jianhui Zhu, Jonathan Kopechek, Brandon Helfield, Francois Yu, Jissy Cyriac, Linda Lavery, Jennifer R Grandis, Flordeliza S Villanueva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanotheranostics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bin QinCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Xucai ChenCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Jianhui ZhuCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Jonathan KopechekCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Brandon HelfieldCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Francois YuCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Jissy CyriacCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Linda LaveryCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
Jennifer R GrandisDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA, USA.
Flordeliza S VillanuevaCenter for Ultrasound for Molecular Imaging and Therapeutics, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA.
University of California, San Francisco · US

Funding

Ultrasound-activated microbubbles for targeted siRNA delivery to tumorR01EB016516 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VILLANUEVA, FLORDELIZA S · 2012 to 2015
$2.3M
High-resolution ultrasound in-vivo animal imaging system-Vevo2100S10RR027383 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KIM, KANG · 2010 to 2010
$498k
Targeted theranostic microbubble vectors for transcription factor decoy deliveryR21CA167373 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VILLANUEVA, FLORDELIZA S · 2012 to 2013
$353k
NCI NIH HHS R21 CA167373NCRR NIH HHS S10 RR027383NIBIB NIH HHS R01 EB016516
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Squamous CellLiposomesAnimalsErbB ReceptorsLuciferasesMiceMicrobubblesRNA, Small InterferingErbB ReceptorsLiposomesLuciferasesRNA, Small InterferingHead and Neck CancerSquamous Cell CarcinomaTumor Growth InhibitionUltrasound Targeted Microbubble Cavitation

Identifiers

PMID38577322
PMCPMC10988211
OpenAlexW4392825412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.