Evidence map›Paper›PMID 38577260›Full record

ArticlePNAS nexus2024

Structural constraints of pyocin S2 import through the ferripyoverdine receptor FpvAI.

Jonathan D Goult, Daniel C L Van, Yasmin V Taylor, Patrick G Inns, Renata Kaminska, Martin Vesely, Colin Kleanthous, Emanuele Paci

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jonathan D GoultDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID https://orcid.org/0000-0001-8513-7054
Daniel C L VanAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.ORCID https://orcid.org/0000-0001-6072-1895
Yasmin V TaylorAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Patrick G InnsDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Renata KaminskaDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID https://orcid.org/0000-0001-7252-379X
Martin VeselyDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID https://orcid.org/0009-0006-3098-8808
Colin KleanthousDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID https://orcid.org/0000-0002-3273-0302
Emanuele PaciDipartimento di Fisica e Astronomia, Università di Bologna, Bologna 40127, Italy.ORCID https://orcid.org/0000-0002-4891-2768
University of Oxford · GBUniversity of Leeds · GBOsservatorio astronomico di Bologna · IT

Funding

Wellcome Trust
6 · The paper itself

Abstract

TonB-dependent transporters (TBDTs) mediate energized transport of essential nutrients into gram-negative bacteria. TBDTs are increasingly being exploited for the delivery of antibiotics to drug-resistant bacteria. While much is known about ground state complexes of TBDTs, few details have emerged about the transport process itself. In this study, we exploit bacteriocin parasitization of a TBDT to probe the mechanics of transport. Previous work has shown that the N-terminal domain of

Identifiers

PMID38577260
PMCPMC10994204
OpenAlexW4393220261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.