Evidence map›Paper›PMID 38577188›Full record

SynthesisWorld journal of gastroenterology2024

Treatment of

Joseph Edwin Kanu, Jonathan Soldera

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 9 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 9 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  10. Trial
  11. Amoxicillin high-dose dual therapy forWorld journal of gastroenterology · 2025
    Trial
  12. Antibiotics (Basel, Switzerland) · 2026
    Review
  13. Review
  14. Article
  15. Efficacy and Safety of Tegoprazan inPharmaceuticals (Basel, Switzerland) · 2026
    Review
  16. Acid peptic disorder compass: An Indian expert consensus on comprehensive management.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Differences and trends in worldwide clinical guidelines forTranslational gastroenterology and hepatology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph Edwin KanuPost Graduate Program at Acute Medicine and Gastroenterology, University of South Wales, Cardiff CF37 1DL, United Kingdom.
Jonathan SolderaPost Graduate Program at Acute Medicine and Gastroenterology, University of South Wales, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com.
University of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo assess the efficacy of regimens containing P-CABs in eradicating

methodsThis study, following PRISMA 2020 guidelines, conducted a systematic review and meta-analysis by searching MEDLINE and Scopus libraries for randomized clinical trials (RCTs) or observational studies with the following command: [("

resultsA total of 256 references were initially retrieved through the search command. Ultimately, fifteen studies (7 RCTs, 7 retrospective observational studies, and 1 comparative unique study) were included, comparing P-CAB triple therapy to PPI triple therapy. The intention-to-treat analysis involved 8049 patients, with 4471 in the P-CAB intervention group and 3578 in the PPI control group across these studies. The analysis revealed a significant difference in

conclusionVPZ-based triple therapy outperformed conventional PPI-based triple therapy in eradicating

Indexed as

Benzene DerivativesHelicobacter InfectionsHelicobacter pyloriImidazolesSulfonamidesAmoxicillinAnti-Bacterial AgentsClarithromycinDrug Therapy, CombinationHumansObservational Studies as TopicProton Pump InhibitorsPyrrolesRandomized Controlled Trials as TopicTreatment Outcome1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamineAmoxicillinAnti-Bacterial AgentsBenzene DerivativesClarithromycinImidazolesProton Pump InhibitorsPyrrolesSulfonamidestegoprazanAmoxicillinHelicobacter pylori infectionPotassium competitive acid blockersProton pump inhibitorsVonoprazan

Identifiers

PMID38577188
PMCPMC10989498
OpenAlexW4392481370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.