Evidence map›Paper›PMID 38577183›Full record

ReviewWorld journal of gastroenterology2024

Prediction, prevention and management of gastroesophageal reflux after per-oral endoscopic myotomy: An update.

Zaheer Nabi, Pradev Inavolu, Nageshwar Reddy Duvvuru

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620899 (Randomized Controlled Trial of Structured Biological Optimization Versus Standard Care With Embedded Prospective Registry in Post-POEM Achalasia Cardia Patients.), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07620899 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Randomized Controlled Trial of Structured Biological Optimization Versus Standard Care With Embedded Prospective Registry in Post-POEM Achalasia Cardia Patients.

TypeinterventionalSponsorAsian Institute of Gastroenterology, IndiaRan2026 to 2028Enrolled166ConditionsAchalasia Cardia, GERD (Gastroesophageal Reflux Disease)ArmsStructured Biological Optimization
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Current practices for endoscopic management of achalasia cardia: A multicenter survey across tertiary care centers in India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Prevention, detection and management of adverse events of third-space endoscopy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zaheer NabiDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, Telangana, India. zaheernabi1978@gmail.com.
Pradev InavoluDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, Telangana, India.
Nageshwar Reddy DuvvuruDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500032, Telangana, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Achalasia cardia, the most prevalent primary esophageal motility disorder, is predominantly characterized by symptoms of dysphagia and regurgitation. The principal therapeutic approaches for achalasia encompass pneumatic dilatation (PD), Heller's myotomy, and the more recent per-oral endoscopic myotomy (POEM). POEM has been substantiated as a safe and efficacious modality for the management of achalasia. Although POEM demonstrates superior efficacy compared to PD and an efficacy parallel to Heller's myotomy, the incidence of gastroesophageal reflux disease (GERD) following POEM is notably higher than with the aforementioned techniques. While symptomatic reflux post-POEM is relatively infrequent, the significant occurrence of erosive esophagitis and heightened esophageal acid exposure necessitates vigilant monitoring to preclude long-term GERD-related complications. Contemporary advancements in the field have enhanced our comprehension of the risk factors, diagnostic methodologies, preventative strategies, and therapeutic management of GERD subsequent to POEM. This review focuses on the limitations inherent in the 24-h pH study for evaluating post-POEM reflux, potential modifications in the POEM technique to mitigate GERD risk, and the strategies for managing reflux following POEM.

Indexed as

Esophageal AchalasiaEsophagitisGastroesophageal RefluxMyotomyNatural Orifice Endoscopic SurgeryEsophageal Sphincter, LowerHumansTreatment OutcomeAchalasia cardiaEsophagitisGastroesophageal refluxGastroesophageal reflux diseasePer-oral endoscopic myotomy

Identifiers

PMID38577183
PMCPMC10989487
OpenAlexW4392481451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.