ArticleWorld journal of gastroenterology2024
Staging liver fibrosis with various diffusion-weighted magnetic resonance imaging models.
Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Precise zonal diagnosis: multi-b-value DWI model reveals differential predictors of clinically significant prostate cancer in peripheral and transition zones.Insights into imaging · 2026Article
- Advanced liver fibrosis detection using a two-stage deep learning approach on standard T2-weighted MRI.Abdominal radiology (New York) · 2026Article
- [Advances and challenges in new technologies for imaging evaluation of liver fibrosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis-A Review of the Literature.Tomography (Ann Arbor, Mich.) · 2025Review
- Histogram analysis of continuous-time random walk and restrictive spectrum imaging for identifying hepatocellular carcinoma and intrahepatic cholangiocarcinoma.Frontiers in oncology · 2025Article
- Exploring the value of arterial spin labeling and six diffusion MRI models in differentiating solid benign and malignant renal tumors.European radiology experimental · 2024Article
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9 authors.
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Abstract
backgroundDiffusion-weighted imaging (DWI) has been developed to stage liver fibrosis. However, its diagnostic performance is inconsistent among studies. Therefore, it is worth studying the diagnostic value of various diffusion models for liver fibrosis in one cohort.
aimTo evaluate the clinical potential of six diffusion-weighted models in liver fibrosis staging and compare their diagnostic performances.
methodsThis prospective study enrolled 59 patients suspected of liver disease and scheduled for liver biopsy and 17 healthy participants. All participants underwent multi-b value DWI. The main DWI-derived parameters included Mono-apparent diffusion coefficient (ADC) from mono-exponential DWI, intravoxel incoherent motion model-derived true diffusion coefficient (IVIM-D), diffusion kurtosis imaging-derived apparent diffusivity (DKI-MD), stretched exponential model-derived distributed diffusion coefficient (SEM-DDC), fractional order calculus (FROC) model-derived diffusion coefficient (FROC-D) and FROC model-derived microstructural quantity (FROC-μ), and continuous-time random-walk (CTRW) model-derived anomalous diffusion coefficient (CTRW-D) and CTRW model-derived temporal diffusion heterogeneity index (CTRW-α). The correlations between DWI-derived parameters and fibrosis stages and the parameters' diagnostic efficacy in detecting significant fibrosis (SF) were assessed and compared.
resultsCTRW-D (
conclusionThe DWI models were similarly valuable in distinguishing SF in patients with liver disease. The combined index of CTRW parameters had the highest AUC.
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