Evidence map›Paper›PMID 38577156›Full record

ArticleFrontiers in nutrition2024

Changes in the consumption of isoflavones, omega-6, and omega-3 fatty acids in women with metastatic breast cancer adopting a whole-food, plant-based diet: post-hoc analysis of nutrient intake data from an 8-week randomized controlled trial.

Jean Lee, Erin K Campbell, Eva Culakova, Lisa M Blanchard, Nellie Wixom, Luke J Peppone, Thomas M Campbell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jean LeeDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, United States.
Erin K CampbellDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, United States.
Eva CulakovaDepartment of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, United States.
Lisa M BlanchardDepartment of Family Medicine, University of Rochester Medical Center, Rochester, NY, United States.
Nellie WixomClinical Research Center, University of Rochester Medical Center, Rochester, NY, United States.
Luke J PepponeDepartment of Surgery, Cancer Control, University of Rochester Medical Center, Rochester, NY, United States.
Thomas M CampbellDepartment of Family Medicine, University of Rochester Medical Center, Rochester, NY, United States.
University of Rochester Medical Center · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

Background: Diets rich in minimally processed plant-based foods are recommended to breast cancer patients, and some may have an interest in whole-food, plant-based (WFPB) diets that avoid animal-based foods, added fats, and refined sugars. Within WFPB diets, the intakes of isoflavones, omega-6 polyunsaturated fatty acids (n-6 PUFAs), and omega-3 polyunsaturated FAs (n-3 PUFAs), which have been discussed in reference to breast cancer outcomes, have not been well characterized. Methods: Women with stage IV breast cancer on stable therapy were randomized 2:1 into (1) a WFPB intervention ( Results: The WFPB intervention participants increased their daily consumption of total isoflavones from a mean of 0.8 mg/day to 14.5 mg/day ( Conclusion: Transitioning to a WFPB diet resulted in significantly increased isoflavone intake and decreased n-6:n-3 ratio in women with breast cancer.

Indexed as

breast cancerisoflavonesomega-3 polyunsaturated fatty acidsomega-6/-3 ratioomega-6 polyunsaturated fatty acidsplant-based dietsoyvegan diet

Identifiers

PMID38577156
PMCPMC10991800
OpenAlexW4393022731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.