Evidence map›Paper›PMID 38577141›Full record

ArticleIndian journal of clinical biochemistry : IJCB2024

Circulating miRNA-21 Levels in Breast Cancer Patients Before and After Chemotherapy and Its Association with Clinical Improvement.

Sanchi Sukhija, Purvi Purohit, Puneet Pareek, Pawan Kumar Garg, Jeewan Ram Vishnoi, Poonam Abhay Elhence, Shobhan Babu Varthya, Praveen Sharma, Sneha Ambwani, Jaykaran Charan

Open access · greenAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sanchi SukhijaDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0003-3549-2669
Purvi PurohitDepartment of Biochemistry, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0001-8559-2911
Puneet PareekDepartment of Radiation Oncology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-6055-9872
Pawan Kumar GargDepartment of Diagnostic and Intervention Radiology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-5805-1869
Jeewan Ram VishnoiDepartment of Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0003-1484-8929
Poonam Abhay ElhenceDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-4660-389X
Shobhan Babu VarthyaDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-7163-0400
Praveen SharmaDepartment of Biochemistry, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-8324-737X
Sneha AmbwaniDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0003-3304-2808
Jaykaran CharanDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India.ORCID 0000-0002-4857-6725
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most frequent type of cancer in women, many patients experience recurrences and metastasis. miR-21 (microRNA-21) as biomarker is under investigation for breast cancer. At present, there is very limited information available regarding effect of chemotherapy on miR-21 expression in breast cancer and its correlation with the clinical improvement. Hence, this study was planned to evaluate the effect of chemotherapy on miR-21 in metastatic breast cancer and its relationship with the clinical outcome. Females, aged-18-90 years diagnosed with Invasive Ductal Carcinoma of breast and candidate of neoadjuvant chemotherapy including Adriamycin (60 mg/m

Indexed as

Breast cancerChemotherapyGene expressionmicroRNA-21RECIST 1.1

Identifiers

PMID38577141
PMCPMC10987404
OpenAlexW4361274806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.