Evidence map›Paper›PMID 38577110›Full record

ArticleiScience2024

Infection induced inflammation impairs wound healing through IL-1β signaling.

Simone Shen, Veronika Miskolci, Colin N Dewey, John-Demian Sauer, Anna Huttenlocher

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  8. Reduced Mortality with Use of Point of Care Cell Suspension Autograft.Journal of burn care & research : official publication of the American Burn Association · 2026
    Article
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  12. Frontiers in veterinary science · 2026
    Article
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  14. Review
  15. Review
  16. Article
  17. Article
  18. Comparative Analysis of Inflammatory Response in Surgical Wound Drainage Fluid in Scoliosis Surgery: A Study of Neuromuscular vs. Idiopathic Patients.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Simone ShenDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
Veronika MiskolciDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
Colin N DeweyDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.
John-Demian SauerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
Anna HuttenlocherDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Cell migration and wound repairR35GM118027 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher · 2016 to 2026
$7.5M
Identification and Characterization of Genes Required for Listeria monocytogenes Cytosolic SurvivalR01AI137070 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2018 to 2022
$2.9M
Metabolic regulation of macrophage-dependent wound healing in vivoR00GM138699 · NIGMS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MISKOLCI, VERONIKA · 2023 to 2025
$739k
Identification of Listeria monocytogenes immune evasion mechanismsR21AI173738 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2023 to 2024
$414k
Metabolic regulation of macrophage-dependent wound healing in vivoK99GM138699 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MISKOLCI, VERONIKA · 2021 to 2022
$200k
NIAID NIH HHS R01 AI137070NIAID NIH HHS R21 AI173738NIGMS NIH HHS K99 GM138699NIGMS NIH HHS R00 GM138699NIGMS NIH HHS R35 GM118027
6 · The paper itself

Abstract

Wound healing is impaired by infection; however, how microbe-induced inflammation modulates tissue repair remains unclear. We took advantage of the optical transparency of zebrafish and a genetically tractable microbe,

Indexed as

Biological sciencesImmune responseImmunologyMicrobiology

Identifiers

PMID38577110
PMCPMC10993181
OpenAlexW4392967100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.