Evidence map›Paper›PMID 38577087›Full record

ArticleWorld journal of gastrointestinal surgery2024

Analysis of the impact of immunotherapy efficacy and safety in patients with gastric cancer and liver metastasis.

Kai Liu, Chun-Xiao Wu, Hui Liang, Tao Wang, Ji-Yuan Zhang, Xiao-Tao Wang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Therapeutic efficacy of immunotherapy for gastric cancer metastasis.World journal of gastrointestinal surgery · 2024
    Article
  3. Article
  4. Role of immunotherapy in gastric cancer with liver metastasis.World journal of clinical oncology · 2024
    Article
  5. Impact of liver metastasis on immunotherapy in gastric carcinoma.World journal of gastrointestinal surgery · 2024
    Article
  6. Article
  7. Article
  8. Consideration on immunotherapy of liver metastases of malignant tumors.World journal of gastrointestinal surgery · 2024
    Article
  9. Article
  10. Impact of immunotherapy on liver metastasis.World journal of gastrointestinal surgery · 2024
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kai LiuDepartment of Radiation and Oncology, Traditional Chinese Hospital of Lu'an affiliated to Anhui University of Traditional Chinese Medicine, Lu'an 237000, Anhui Province, China.
Chun-Xiao WuDepartment of Gastroenterology, Ehu branch of Xishan People's Hospital of Wuxi City, Wuxi 214116, Jiangsu Province, China.
Hui LiangDepartment of Radiation and Oncology, Traditional Chinese Hospital of Lu'an affiliated to Anhui University of Traditional Chinese Medicine, Lu'an 237000, Anhui Province, China.
Tao WangDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510400, Guangdong Province, China.
Ji-Yuan ZhangDepartment of Gastrointestinal Surgery, Hunan Provincial People's Hospital, Changsha 410002, Hunan Province, China.
Xiao-Tao WangDepartment of Traditional Chinese medicine, Ehu branch of Xishan People's Hospital of Wuxi City, Wuxi 214116, Jiangsu Province, China. wxtxyjc@163.com.
Anhui University of Traditional Chinese Medicine · CNWuxi Taihu Hospital · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNHunan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) is the fifth most common type of cancer and has the fourth highest death rate among all cancers. There is a lack of studies examining the impact of liver metastases on the effectiveness of immunotherapy in individuals diagnosed with GC.

aimTo investigate the influence of liver metastases on the effectiveness and safety of immunotherapy in patients with advanced GC.

methodsThis retrospective investigation collected clinical data of patients with advanced stomach cancer who had immunotherapy at our hospital from February 2021 to January 2023. The baseline attributes were compared using either the Chi-square test or the Fisher exact probability method. The chi-square test and Kaplan-Meier survival analysis were employed to assess the therapeutic efficacy and survival duration in GC patients with and without liver metastases.

resultsThe analysis comprised 48 patients diagnosed with advanced GC, who were categorized into two groups: A liver metastasis cohort (

conclusionImmunotherapy is less effective in GC patients with liver metastases compared to those without liver metastasis.

Indexed as

Effectiveness of treatmentGastric cancerSpread of cancer to the liverTreatment with immunotherapy

Identifiers

PMID38577087
PMCPMC10989337
OpenAlexW4393040937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.