Evidence map›Paper›PMID 38577075›Full record

ArticleWorld journal of gastrointestinal surgery2024

Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn's disease.

Phillip Gu, Shishir Dube, Norman Gellada, So Yung Choi, Susan Win, Yoo Jin Lee, Shaohong Yang, Talin Haritunians, Gil Y Melmed, Eric A Vasiliauskas and 11 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 2 countries.

Phillip GuDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States. phillipgu12@gmail.com.
Shishir DubeDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Norman GelladaDepartment of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
So Yung ChoiDepartment of Biostatistics Shared Resource, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Susan WinDepartment of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Yoo Jin LeeDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu 42601, South Korea.
Shaohong YangDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Talin HarituniansDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Gil Y MelmedDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Eric A VasiliauskasDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Niru BonthalaDepartment of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, United States.
Gaurav SyalDepartment of Medicine, University of California at San Diego, San Diego, CA 92093, United States.
Andres J YarurDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
David ZiringDepartment of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Shervin RabizadehDepartment of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Phillip FleshnerDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Cindy KallmanDepartment of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Suzanne DevkotaDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Stephan R TarganDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Dalin LiDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Dermot Pb McGovernDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, United States.
Cedars-Sinai Medical Center · USKeimyung University · KRUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence suggests inflammatory mesenteric fat is involved in post-operative recurrence (POR) of Crohn's disease (CD). However, its prognostic value is uncertain, in part, due to difficulties studying it non-invasively.

aimTo evaluate the prognostic value of pre-operative radiographic mesenteric parameters for early endoscopic POR (ePOR).

methodsWe conducted a retrospective cohort study of CD subjects ≥ 12 years who underwent ileocecal or small bowel resection between 1/1/2007 to 12/31/2021 with computerized tomography abdomen/pelvis ≤ 6 months pre-operatively and underwent ileocolonoscopy ≤ 15 months post-operatively. Visceral adipose tissue (VAT) volume (cm

resultsOf the 139 subjects included, 45% of subjects developed early ePOR (

conclusionVAT radiodensity is potentially a novel non-invasive prognostic imaging marker to help risk stratify CD patients for POR.

Indexed as

Computed tomographyCreeping fatCrohn’s diseaseMesenteric adipose tissueSurgeryVisceral adipose tissue

Identifiers

PMID38577075
PMCPMC10989343
OpenAlexW4393041117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.