Evidence map›Paper›PMID 38576882›Full record

ArticlePreventive nutrition and food science2024

Protective Effects of Cereal Grain Extracts on Alcohol-Induced Hepatocyte Damage.

Jinhee Song, Jaemin Lee, Hana Lee, Heon Sang Jeong, Junsoo Lee, Younghwa Kim

Open access · hybridAbstract read
In one paragraph

Article in Preventive nutrition and food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jinhee Song *Department of Food Science and Biotechnology, Chungbuk National University, Chungbuk 28644, Korea.ORCID https://orcid.org/0000-0002-9256-5679
Jaemin Lee *Department of Food Science and Biotechnology, Chungbuk National University, Chungbuk 28644, Korea.ORCID https://orcid.org/0009-0003-3910-9388
Hana LeeDepartment of Food Science and Biotechnology, Chungbuk National University, Chungbuk 28644, Korea.ORCID https://orcid.org/0000-0002-4059-4195
Heon Sang JeongDepartment of Food Science and Biotechnology, Chungbuk National University, Chungbuk 28644, Korea.ORCID https://orcid.org/0000-0003-0349-4483
Junsoo LeeDepartment of Food Science and Biotechnology, Chungbuk National University, Chungbuk 28644, Korea.ORCID https://orcid.org/0000-0001-5557-4229
Younghwa KimDepartment of Food Science and Biotechnology, Kyungsung University, Busan 48434, Korea.ORCID https://orcid.org/0000-0003-4186-887X
Chungbuk National University · KRKyungsung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the protective effects of cereal grains on alcohol-induced hepatocyte damage. Cereal grains were extracted with methanol, and their radical scavenging properties and total phenolic contents were examined. Black rice extract exhibited the highest total polyphenol content and radical scavenging capacity. Treatment with sorghum extract increased the viability of cells exposed to alcohol by up to 81.6%. All cereal grain extracts decreased reactive oxygen species and malondialdehyde production and glutathione depletion in HepG2 cells exposed to ethanol. In particular, black rice and sorghum extracts exhibited greater antioxidant effects than other cereal grains. Treatment with black rice extract increased the levels of alanine aminotransferase and aspartate aminotransferase of alcohol-exposed cells to control levels. Overall, black rice extract showed a greater protective effect compared with other cereal grains against alcohol exposure in HepG2 cells and could improve alcohol-induced liver problems.

Indexed as

cytoprotectionethanolgrainHepG2 cellsoxidative stress

Identifiers

PMID38576882
PMCPMC10987386
OpenAlexW4393268498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.