Evidence map›Paper›PMID 38576620›Full record

ReviewFrontiers in immunology2024

From gut to brain: understanding the role of microbiota in inflammatory bowel disease.

Siyu Wang, Shuwei Zhou, Zhongyu Han, Bin Yu, Yin Xu, Yumeng Lin, Yutong Chen, Zi Jin, Yalong Li, Qinhan Cao and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Flavonoid Extract ofAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Emotional Disturbances and Crohn's Disease.Clinical practice and epidemiology in mental health : CP & EMH · 2025
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Siyu Wang *Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Shuwei Zhou *Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zhongyu Han *Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Bin YuDepartment of Gastroenterology, The First Hospital of Hunan University of Chinese Medicine, Changsha, China.
Yin XuDepartment of Gastroenterology, The First Hospital of Hunan University of Chinese Medicine, Changsha, China.
Yumeng LinEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yutong ChenThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Zi JinDepartment of Anesthesiology and Pain Rehabilitation, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, China.
Yalong LiAnorectal Department, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, China.
Qinhan CaoSchool of Clinical Medicine, Chengdu University of Traditional Chinese Medicine (TCM), Chengdu, China.
Yunying XuClinical Medical School, Affiliated Hospital of Chengdu University, Chengdu, China.
Qiang ZhangDepartment of Gastroenterology, The First Hospital of Hunan University of Chinese Medicine, Changsha, China.
Yuan-Cheng WangZhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNZhongda Hospital Southeast University · CNChengdu University of Traditional Chinese Medicine · CNShanghai Sunshine Rehabilitation Center · CNYunnan University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the proposal of the "biological-psychological-social" model, clinical decision-makers and researchers have paid more attention to the bidirectional interactive effects between psychological factors and diseases. The brain-gut-microbiota axis, as an important pathway for communication between the brain and the gut, plays an important role in the occurrence and development of inflammatory bowel disease. This article reviews the mechanism by which psychological disorders mediate inflammatory bowel disease by affecting the brain-gut-microbiota axis. Research progress on inflammatory bowel disease causing "comorbidities of mind and body" through the microbiota-gut-brain axis is also described. In addition, to meet the needs of individualized treatment, this article describes some nontraditional and easily overlooked treatment strategies that have led to new ideas for "psychosomatic treatment".

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesMental DisordersMicrobiotaBrainHumansbrain-gut-microbiota axiscomorbidities of mind and bodyinflammatory bowel diseasepsychological disorderstreatment strategy

Identifiers

PMID38576620
PMCPMC10991805
OpenAlexW4393053283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.