Evidence map›Paper›PMID 38576615›Full record

ArticleFrontiers in immunology2024

Identification of a new genetic variant (G231N, E232T, N235D) of peptidylarginine deiminase from

Grzegorz P Bereta, Karolina Strzelec, Katarzyna Łazarz-Bartyzel, Agata Dziedzic-Kowalska, Zuzanna Nowakowska, Anna Krutyhołowa, Ewa Bielecka, Tomasz Kantyka, Aleksander M Grabiec, Tomasz Kaczmarzyk and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Pathogenesis ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Pathogenicity ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Polymorphic Variants of Peptidylarginine Deiminase Gene fromInternational journal of molecular sciences · 2025
    Article
  5. Impact of increasedJournal of oral microbiology · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Grzegorz P BeretaMalopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.
Karolina StrzelecDepartment of Molecular Biology and Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.
Katarzyna Łazarz-BartyzelDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Faculty of Medicine, Medical College, Jagiellonian University, Krakow, Poland.
Agata Dziedzic-KowalskaDepartment of Molecular Biology and Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.
Zuzanna NowakowskaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Anna KrutyhołowaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Ewa BieleckaMalopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.
Tomasz KantykaMalopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.
Aleksander M GrabiecDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Tomasz KaczmarzykDepartment of Oral Surgery, Medical College, Jagiellonian University, Krakow, Poland.
Maria Chomyszyn-GajewskaDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Faculty of Medicine, Medical College, Jagiellonian University, Krakow, Poland.
Jan Potempa *Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Katarzyna Gawron *Department of Molecular Biology and Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland.
Jagiellonian University · PLMedical University of Silesia · PL

Funding

Bacterial peptidylarginine deiminase, a link between gums and joint diseaseR01DE022597 · NIDCR · UNIVERSITY OF LOUISVILLE · PI POTEMPA, JAN S · 2013 to 2023
$3.7M
NIDCR NIH HHS R01 DE022597
6 · The paper itself

Abstract

Chronic periodontitis (CP), an inflammatory disease of periodontal tissues driven by a dysbiotic subgingival bacterial biofilm, is also associated with several systemic diseases, including rheumatoid arthritis (RA).

Indexed as

Chronic PeriodontitisPorphyromonas gingivalisHumansPeptidesPeriodontiumProtein-Arginine DeiminasesPeptidesProtein-Arginine Deiminaseschronic periodontitisdisease prognosisgenetic variabilitypeptidylarginine deiminaseP. gingivalispolymorphic variant(s)virulence

Identifiers

PMID38576615
PMCPMC10991804
OpenAlexW4393053281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.