Evidence map›Paper›PMID 38576535›Full record

ArticleFrontiers in neurology2024

Case report: Simultaneous measurement of intracranial pressure and lumbar intrathecal pressure during epidural patch therapy for treating spontaneous intracranial hypotension syndrome. Spontaneous intracranial hypotension or spontaneous intraspinal hypovolume?

Nicolas Engrand, Quentin Salardaine, Jean-Philippe Desilles, Cécile Echard, Pierre Bourdillon, Marc Williams, Guillaume Baille

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nicolas Engrand *Neuro-Intensive Care Unit-Anesthesiology, Rothschild Foundation Hospital, Paris, France.
Quentin SalardaineNeurology Department, Delafontaine Hospital, Saint-Denis, France.
Jean-Philippe DesillesInterventional Neuroradiology Department, Rothschild Foundation Hospital, Paris, France.
Cécile EchardNeuro-Intensive Care Unit-Anesthesiology, Rothschild Foundation Hospital, Paris, France.
Pierre Bourdillon *Neurosurgery Department, Rothschild Foundation Hospital, Paris, France.
Marc WilliamsDiagnostic Neuroradiology Department, Rothschild Foundation Hospital, Paris, France.
Guillaume BailleNeurology Department, Delafontaine Hospital, Saint-Denis, France.
Fondation de Rothschild · FRCentre Hospitalier Saint-Denis · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Spontaneous intracranial hypotension (SIH) is frequently complicated by subacute subdural hematoma (SDH) and more rarely by bilateral thalamic ischemia. Here, we report a case of SIH-related SDH treated with three epidural patches (EPs), with follow-up of the intracranial pressure and lumbar intrathecal pressure. Methods: A 46-year-old man presented bilateral thalamic ischemia, then a growing SDH. After failure of urgent surgical evacuation, he underwent three saline EPs, two dynamic myelography examinations and one digital subtraction angiography-phlebography examination. However, because of no dural tear and no obstacle to the venous drainage of the vein of Galen, no therapeutic procedure was available, and the patient died. Results: The case exhibited a progressive increase in the transmission of lumbar intrathecal pressure to intracranial pressure during the three EPs. The EPs may have successfully treated the SIH, but the patient did not recover consciousness because of irreversible damage to both thalami. Conclusion: Clinicians should be aware of the bilateral thalamic ischemia picture that may be the presenting sign of SIH. Moreover, the key problem in the pathophysiology of SIH seems to be intraspinal and intracranial volumes rather than pressures. Therefore, intracranial hypotension syndrome might actually be an intraspinal hypovolume syndrome.

Indexed as

bithalamic ischemiacase reportepidural patchspontaneous intracranial hypotensionsubacute subdural hematoma

Identifiers

PMID38576535
PMCPMC10991849
OpenAlexW4393054408

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.